The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
In adults (with depression)
- Dry mouth
- Blurry vision
- Nausea
- Vomiting
- Constipation
- Sleepiness
- Dizziness
- Confusion
- Anxiety
- Restlessness
In children (with bedwetting problems)
- Nervousness
- Sleep problems
- Tiredness
- Stomach upset
Less Common Side Effects
In adults (with depression)
- Numbness or tingling
- Ringing in the ears
- Change in taste
- Weight gain or loss
- Sweating
- Changes in blood pressure
- Fast or irregular heartbeat
- Mood changes
In children (with bedwetting problems)
- Constipation
- Anxiety
- Fainting
Tofranil serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Suicidal thoughts or behaviors
- Heart attack: chest pain, cold sweats, left arm pain, trouble breathing
- Stroke: sudden numbness, weakness, confusion, trouble talking
- Serious allergic reaction: difficulty breathing, hives, itching, fast heartbeat, tightness in the throat, dizziness, swelling in the face or tongue
Source: DailyMed
More on Tofranil side effects
The following Tofranil side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
Abdominal or stomach pain
agitation
blurred vision
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chest pain or discomfort
clay-colored stools
cold sweats
confusion about identity, place, and time
continuing ringing or buzzing or other unexplained noise in the ears
cough or hoarseness
dark urine
decrease in the frequency of urination
difficulty in passing urine (dribbling)
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
double vision
false beliefs that cannot be changed by facts
fast, pounding, or irregular heartbeat or pulse
feeling, seeing, or hearing things that are not there
feeling that others are watching you or controlling your behavior
feeling that others can hear your thoughts
fever with or without chills
flushed, dry skin
general feeling of tiredness or weakness
hearing loss
hostility
hyperventilation
inability to move the arms, legs, or facial muscles
irritability
itching or rash
lack of coordination
lethargy
loss of balance control
lower back or side pain
mood or mental changes
muscle spasm or jerking of all extremities
muscle trembling, jerking, or stiffness
nightmares
pain or discomfort in the arms, jaw, back, or neck
painful or difficult urination
pinpoint red or purple spots on the skin
rapid weight gain
redness of the face, neck, arms, and occasionally, upper chest
restlessness
seizures
shakiness and unsteady walk
slow speech
stiffness of the limbs
stupor
sweating
swelling of the face, ankles, legs, or hands
talking, feeling, and acting with excitement
trouble sleeping
twisting movements of the body
uncontrolled movements, especially of the face, neck, and back
unusual behavior
unusual tiredness or weakness
weakness in the arms, hands, legs, or feet
yellow eyes or skin
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Bluish color of fingernails, lips, skin, palms, or nail beds
cold, clammy skin
decreased awareness or responsiveness
difficult or troubled breathing
disorientation
fast, weak pulse
hallucinations
irregular, fast, slow, or shallow breathing
severe sleepiness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Bigger, dilated, or enlarged pupils (black part of the eye)
black tongue
decreased interest or ability in sexual intercourse
difficulty having a bowel movement (stool)
enlargement of the breast
hives or welts
increase in sexual ability, desire, drive, or performance
increased sensitivity of the eyes to light
increased urge to urinate during the night
peculiar taste
redness or other discoloration of the skin
severe sunburn
swelling of the testicles
swelling of the breasts or breast soreness in both females and males
swollen, painful, or tender lymph glands on the side of the face or neck
unexpected or excess milk flow from the breasts
waking to urinate at night
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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