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Copiktra

Copiktra Side Effects

Allison Baxley, PharmD, BCOPConnie Zheng, PharmD
Reviewed by Allison Baxley, PharmD, BCOP, Connie Zheng, PharmD
Last reviewed on January 28, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Low white blood cells (up to 63%)
  • Diarrhea, including colitis (up to 57%)
  • Low red blood cells (up to 45%)
  • High liver enzymes (up to 40%)
  • Low platelet levels (39%)
  • Rash (31%)
  • Electrolyte changes in blood (up to 31%)
  • Tiredness (up to 29%)
  • Fever (up to 29%)
  • Respiratory infections (up to 28%)
  • Cough (25%)

Less Common Side Effects

  • Constipation
  • Nausea or vomiting
  • Headache
  • Muscle pain
  • Joint pain
  • Trouble catching your breath
  • Mouth sores

Copiktra serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious lung problems: cough, trouble breathing, fever, chest pain
  • Infection: fever, body aches, severe tiredness, trouble breathing, cough
  • Serious skin reactions: painful blisters, skin wounds, peeling skin, fever, sore throat, body aches
  • Severe diarrhea: more than 6 stools over what’s normal for you, fever, severe stomach pain, blood in stool

Source: DailyMed

The following Copiktra side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Dry cough, shortness of breath or trouble breathing
  • Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
  • Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
  • Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
  • Rash, fever, and swollen lymph nodes
  • Redness, blistering, peeling, or loosening of the skin, including inside the mouth
  • Severe or prolonged diarrhea
  • Sudden or severe stomach pain, bloody diarrhea, fever, nausea, vomiting
  • Unusual bruising or bleeding

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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