Medications for pancreatic insufficiency are used to treat exocrine pancreatic insufficiency that's due to certain health conditions like chronic pancreatitis. They work by providing your body with the digestive enzymes that your pancreas can't produce enough of. These medications help you digest fats, proteins, and carbohydrates. Common classes include pancreatic enzyme replacements. Examples are pancrelipase (Creon, Pancreaze, Zenpep) and they're usually taken as oral capsules. These treatments help improve your digestion and nutrient absorption.