Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Tecentriq vs. Tecentriq Hybreza

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Tecentriq (atezolizumab)
    Tecentriq hybreza
  • Tecentriq (atezolizumab)
    Tecentriq hybreza

  • Summary of Tecentriq vs. Tecentriq Hybreza

    Summary for PD-L1 inhibitor
    Prescription only

    Tecentriq (atezolizumab) is an immunotherapy medication that’s used to treat several different types of cancer, like lung cancer, liver cancer, and melanoma. It turns on your immune system to fight cancer. But this can sometimes cause side effects like rash, diarrhea, and lung problems that might need temporary treatment with corticosteroids. Tecentriq (atezolizumab) is given through the vein (intravenously, IV) at an infusion center or provider’s office.

    Summary for PD-L1 inhibitor
    Prescription only

    Tecentriq Hybreza (atezolizumab / hyaluronidase) is an immunotherapy cancer medication that’s given as an injection under the skin. It’s FDA approved for some adults with lung cancer, liver cancer, or melanoma. It can also help treat people 12 years and older with alveolar soft part sarcoma (ASPS). A nurse will give the injection into the thigh every 3 weeks at a clinic. Side effects include tiredness, muscle or bone pain, and cough. Depending on your cancer type and treatment plan, you might take Tecentriq Hybreza on its own or with other chemotherapy.

  • Indications of Tecentriq vs. Tecentriq Hybreza

    Indications for
    •Non-small cell lung cancer (NSCLC)
    •Early-stage cancer that’s had surgery and chemotherapy, given by itself
    •Cancer that has spread (metastatic), given by itself or with chemotherapy
    •Advanced small cell lung cancer (SCLC), given with chemotherapy
    •Certain liver cancers that can’t be surgically removed or has spread, given with Avastin (bevacizumab)
    •Advanced melanoma in people with a specific mutation, given with other targeted therapy
    •Advanced alveolar soft part sarcoma (ASPS)
    Indications for

    Certain types of:

    •Non-small cell lung cancer (NSCLC) in adults
    •Small cell lung cancer (SCLC) in adults
    •Liver cancer in adults
    •Melanoma in adults
    •Alveolar soft part sarcoma (ASPS) in people 12 years and older weighing 88 lbs or more

  • Pros and Cons of Tecentriq vs. Tecentriq Hybreza

    Pros and Const for PD-L1 inhibitor
    Pros
    •Doesn’t cause side effects, like nausea, vomiting, and hair loss, that are common with traditional chemotherapy
    •First-choice treatment option for certain small-cell and non-small-cell lung and liver cancers
    •Uses your body’s own immune system to fight cancer
    Cons
    •Might cause immune-related side effects like diarrhea, rash, and lung problems
    •Might require treatment breaks and a corticosteroid to manage side effects
    •Given through an IV, which requires using a needle
    Pros and Const for PD-L1 inhibitor
    Pros
    •Given as an injection under the skin that takes a few minutes
    •Given every 3 weeks
    Cons
    •Must be given by a healthcare professional
    •Risk of reactions like chills or flushing during the injection

  • Common Side Effects of Tecentriq vs. Tecentriq Hybreza

    Common Side Effects for
    •Low red blood cells (anemia; up to 69%)
    •Other abnormal lab test results (up to 48%)
    •Low white blood cells (up to 49%)
    •Tiredness (up to 44%)
    •Higher liver enzyme levels in blood (up to 38%)
    •Cough (up to 26%)
    •Lower appetite (up to 23%)
    •Trouble breathing (up to 22%)
    •Muscle pain (up to 20%)
    •Nausea (up to 18%)
    Common Side Effects for
    •Low hemoglobin levels (67%)
    •Low white blood cells (37%)
    •Low sodium levels (46%)
    •Higher liver enzyme levels (up to 33%)
    •Low calcium levels (22%)
    •High potassium levels (21%)
    •High calcium levels (20%)
    •Tiredness (19%)
    •Muscle or bone pain (15%)

  • Warnings of Tecentriq vs. Tecentriq Hybreza

    Common Side Effects for
    •Immune-related side effects
    •Infusion reactions
    •Stem cell transplant complications
    •Harm to unborn baby
    Common Side Effects for
    •Immune-related side effects
    •Injection-related reactions
    •Complications from stem cell transplants
    •Harm to an unborn baby

  • Prices with our coupons for Tecentriq vs. Tecentriq Hybreza

    Learn more about Tecentriq
    Learn more about Tecentriq hybreza

Compare other Lung Cancer drugs

Keytruda vs TecentriqImfinzi vs KeytrudaJemperli vs KeytrudaKeytruda vs OpdivoLibtayo vs KeytrudaRybrevant vs TagrissoTagrisso vs Keytruda
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.