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Suprax vs. Cipro

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Cefixime (Suprax) and Ciprofloxacin (Cipro) are both antibiotics used to treat bacterial infections, but they belong to different classes and have distinct uses and side effects. Cefixime is a cephalosporin antibiotic that works by preventing bacteria from forming their protective covering, making it effective for infections like urinary tract infections, ear infections, and gonorrhea. Ciprofloxacin, on the other hand, is a fluoroquinolone antibiotic that kills bacteria by blocking enzymes they need to grow and repair their DNA. It is used for more serious infections such as skin, bone, and joint infections, as well as anthrax and plague. While both medications can cause nausea and diarrhea, Ciprofloxacin has more severe potential side effects, including tendon rupture and nerve damage, and is usually reserved for more serious infections or when other options are not available. Cefixime is generally taken once a day, whereas Ciprofloxacin is typically taken twice daily. Additionally, Ciprofloxacin interacts with many medications and can make your skin more sensitive to the sun, requiring extra precautions.

Cefixime

(Suprax)

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Ciprofloxacin

(Cipro)

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Summary for Suprax

Prescription only

Cefixime (Suprax) is a cephalosporin antibiotic that treats many types of bacterial infections, but it tends to cause diarrhea and stomach upset, and is more expensive than other similar antibiotics.

Indications for Suprax

  • Urinary tract infections
  • Ear infections (otitis media)
  • Throat and tonsil infections (strep throat, tonsillitis)
  • Bronchitis with bacterial infection
  • Gonorrhea

Pros and Cons for Suprax

Pros

  • Treats many types of bacterial infections
  • May be a good choice for people who have gonorrhea and don't like getting shots
  • Available as a suspension and chewable tablet for people who cannot swallow pills
  • Can be taken once a day, which is convenient
  • Available as a generic

Cons

  • About 30% of people who take cefixime (Suprax) experience a stomach or intestinal side effect, such as nausea and diarrhea.
  • Not recommended to be used for the cold or flu, or for bronchitis that is not bacterial
  • If you're allergic to penicillins or other cephalosporin antibiotics, you might not be able to take this medicine.
  • Though it is available as a generic, cefixime (Suprax) costs more than other antibiotics that are used for the same types of infections.

Common Side Effects for Suprax

  • Diarrhea (16%)
  • Nausea (7%)
  • Loose or frequent stools (6%)
  • Passing gas (4%)
  • Abdominal pain (3%)
  • Indigestion (3%)

Warnings for Suprax

  • ALLERGIC REACTION
  • C. DIFFICILE DIARRHEA
  • KIDNEY PROBLEMS
  • HIGHER RISK OF BLEEDING
  • DRUG-RESISTANT BACTERIA
  • PHENYLKETONURIA (PKU) PROBLEMS

Summary for Cipro

Prescription only

Ciprofloxacin (Cipro) is a fluoroquinolone antibiotic. It can treat many types of bacterial infections, including sinus infections and urinary tract infections (UTIs). But because ciprofloxacin (Cipro) can cause serious side effects, such as tendon rupture and nerve damage, it's usually only prescribed for more serious infections or when there aren't any safer options. Ciprofloxacin (Cipro) is taken by mouth, typically twice daily. It's available as a pill and oral solution. Some of the more common side effects of this medication include nausea and diarrhea.

Indications for Cipro

Adults only

Adults and children

Pros and Cons for Cipro

Pros

  • Can take with or without food
  • Available as tablets, oral liquid, and injection
  • Possible option for people with penicillin allergy

Cons

Common Side Effects for Cipro

  • Nausea
  • Diarrhea
  • Vomiting
  • Rash
  • Abnormal liver blood test results

Warnings for Cipro

  • Tendon inflammation and rupture
  • Effects on the brain, nerves, and mental health
  • Worsening of myasthenia gravis
  • Severe allergic and skin reactions
  • Liver damage
  • Severe damage to a major blood vessel
  • Infectious diarrhea
  • Life-threatening abnormal heart rhythm (QT prolongation)
  • Muscle, bone, or joint problems in children
  • Sun and light sensitivity
  • Kidney problems

Prices with our coupons for Suprax vs. Cipro

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Cefixime2 capsules / 400mg
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Ciprofloxacin14 tablets / 500mg
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