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Oxymetazoline vs. Phenylephrine

Oxymetazoline (Afrin) is a nasal decongestant spray. More specifically, it's an alpha-1 receptor agonist. Oxymetazoline (Afrin) is sprayed into the nostrils up to twice daily to help relieve stuffy noses. But you should avoid using it for longer than 3 days in a row because doing so can raise the risk for rebound congestion. There are oxymetazoline products for children and adults that differ in dosage, so read the label on your specific product to make sure it's appropriate for you. Some side effects of this medication might include mild burning or stinging in the nose.

• Short-term relief of nasal and sinus congestion and pressure

• Burning in the nose
• Stinging in the nose
• Rebound nasal congestion (if using longer than 3 days)

• Rebound congestion
• Might not be safe for people with certain medical conditions
• For use in the nose only

Phenylephrine eye drops are used to dilate (widen) pupils for eye exams or certain eye procedures. Side effects include temporary burning or stinging in the eye, blurry vision, and possibly raise your blood pressure. Let your provider know if your pregnant or breastfeeding because you might need to use a different medication.

• Dilate (widen) pupils

• Temporary stinging or burning in your eye
• Temporary blurry vision
• Sensitivity to light

• For use in the eyes only
• Heart problems
• High blood pressure
• Rebound pupil constriction