Opdivo
(nivolumab)
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Summary for Opdivo
Opdivo (nivolumab) is a type of immunotherapy medication used to treat many types of cancer. They can include melanoma, lung cancer, kidney cancer, colon cancer, and others. Opdivo (nivolumab) is given as infusion through the vein (IV) every few weeks at an infusion center. This medication can cause side effects, like rash, diarrhea, and breathing problems. Depending on the cancer treated, Opdivo (nivolumab) can be used by itself or with other therapies.
Indications for Opdivo
Certain types of:
- Melanoma
- Non-small cell lung cancer (NSCLC)
- Pleural mesothelioma (cancer of the lining of the lungs)
- Renal cell carcinoma (kidney cancer)
- Hodgkin lymphoma
- Head and neck cancer
- Bladder cancer
- Colorectal cancer
- Liver cancer
- Esophageal cancer
- Stomach cancer
Pros and Cons for Opdivo
Pros
- Less common to have nausea, vomiting, and hair loss than traditional chemotherapy
- Recommended first-choice treatment for certain people with melanoma and esophageal cancer
- Given every few weeks
Cons
- Given as an infusion through the vein that takes at least 30 minutes
- Might cause immune-related side effects like diarrhea, rash, and lung problems
- Might need to take breaks from treatment and take a steroid to manage some side effects
Common Side Effects for Opdivo
- Tiredness (59%)
- Higher blood sugar levels (46%)
- Muscle or bone pain (42%)
- Anemia (low red blood cell count; 41%)
- Low white blood cell count (41%)
- Rash (40%)
- Diarrhea (36%)
- Nausea (30%)
- Higher liver enzyme levels (up to 29%)
- Cough (28%)
- Lower appetite (22%)
- Upper respiratory tract infection (22%)
- Vomiting (20%)
Warnings for Opdivo
- Immune-related side effects
- Infusion-related reactions
- Complications from stem cell transplants
- Harm to an unborn baby
Summary for Opdivo Qvantig
Opdivo Qvantig (nivolumab / hyaluronidase) is an injection that’s given under the skin. It’s an immunotherapy medication approved to treat adults with certain cancers, like melanoma and kidney cancer. A healthcare professional will help inject it into your stomach or thigh at a clinic every few weeks. Opdivo Qvantig can cause side effects like rash, trouble breathing, and diarrhea. It can also cause injection site reactions like redness or swelling. Depending on the type of cancer you have, it might be used alone or with other treatments.
Indications for Opdivo Qvantig
Certain types of:
Pros and Cons for Opdivo Qvantig
Pros
- Given as an injection under the skin that takes a few minutes
- Given every few weeks
- Less common to have nausea, vomiting, and hair loss than traditional chemotherapy
Cons
- Must be given by a healthcare professional
- Might cause side effects like rash, coughing, diarrhea, and injection site reactions
- Not approved for children
Common Side Effects for Opdivo Qvantig
- Lower hemoglobin levels (46%)
- Higher creatinine levels (38%)
- Lower white blood cells (36%)
- Lower sodium levels (34%)
- Higher potassium levels (34%)
- Higher liver enzyme levels (up to 32%)
- Muscle, bone, or joint pain (31%)
- Higher calcium levels (29%)
- Tiredness (20%)
- Itchiness (16%)
- Rash (15%)
- Hypothyroidism (low thyroid hormone levels; 12%)
- Cough (11%)
- Diarrhea (11%)
- Stomach pain (10%)
Warnings for Opdivo Qvantig
- Immune-related side effects
- Complications from stem cell transplants
- Harm to an unborn baby
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