Key takeaways
PEG 3350/electrolytes (Golytely, Nulytely, Moviprep, Plenvu, Gavilyte) and Suprep (sodium sulfate/potassium sulfate/magnesium sulfate) are both osmotic laxatives used to clean the colon before a colonoscopy. They work by pulling water into the intestines to cause diarrhea, which helps clear the colon. However, they differ in several ways. PEG 3350/electrolytes is available in multiple brands and requires you to drink a large volume of liquid, ranging from 1 to 4 liters, depending on the brand. Suprep, on the other hand, requires less liquid, with two 6-ounce doses mixed with water. PEG 3350/electrolytes can be used in children as young as 6 months for some brands, while Suprep is approved for children 12 years and older. Common side effects for both include nausea and bloating, but Suprep may also cause a gout attack and is not recommended for people with kidney problems. Additionally, Suprep has a berry flavor, while PEG 3350/electrolytes may come with flavor packets. Both medications can cause serious side effects like dehydration and electrolyte imbalances, so it's important to stay hydrated and follow your healthcare provider's instructions carefully.
