Skip to main content

VMAT2 Inhibitors

VMAT2 inhibitors are used to treat chorea or uncontrolled movements associated with Huntington's disease. They work by reducing the activity of certain chemicals in the brain, specifically dopamine, which is thought to lessen the symptoms of chorea.

Why are vmat2 inhibitors prescribed?

  1. Huntington's Chorea (98%)
  2. Tardive Dyskinesia (2%)

Key takeaways

VMAT2 inhibitors are used to treat health conditions such as tardive dyskinesia and Huntington's disease. VMAT2 inhibitors are thought to work by blocking the vesicular monoamine transporter 2 (VMAT2) protein, which helps to reduce the amount of dopamine and other chemicals in the brain, thereby mangaging involuntary movements. These medications are available in oral forms, including tablets and capsules. Examples include tetrabenazine (Xenazine), deutetrabenazine (Austedo, Austedo XR), and valbenazine (Ingrezza, Ingrezza Sprinkle).

Prices for popular VMAT2 Inhibitors medications
Viewing 5 of 5 medications
TETRABENAZINE treats chorea, a condition that causes uncontrolled body movements. It works by balancing substances in your brain that help manage body movements and coordination.
tablet icon

Austedo

as low as$4,790
DEUTETRABENAZINE treats movement disorders, such as tardive dyskinesia (TD) and chorea. It works by balancing substances in your brain that help manage body movements and coordination.
DEUTETRABENAZINE treats movement disorders, such as tardive dyskinesia (TD) and chorea. It works by balancing substances in your brain that help manage body movements and coordination.
Ingrezza Sprinkle is only available as a brand name drug.
VALBENAZINE treats movement disorders, such as tardive dyskinesia (TD) and chorea. It works by balancing substances in your brain that help manage body movements and coordination.
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

Subscribe and save

Get prescription saving tips and more from GoodRx Health. Enter your email to sign up

By signing up, I agree to GoodRx’s Terms of Use and Privacy Policy, and to receive marketing messages from GoodRx.

Latest Articles

Browse medications

View All
Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.