Key takeaways:
Glucagon-like peptide-1 (GLP-1) receptor agonists include medications such as Ozempic (semaglutide) and Trulicity (dulaglutide). Zepbound (tirzepatide) and Mounjaro (tirzepatide) are considered glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonists.
GLP-1 and GIP/GLP-1 receptor agonists are used to treat Type 2 diabetes, lower the risk of major cardiovascular and kidney-related events, and/or to help people manage their body weight, among other uses. Most are injections, but there’s one oral option available.
The best way to save on GLP-1 and GIP/GLP-1 receptor agonists is to use your health insurance. But coverage can depend on your specific plan, health history, and other factors. If your cost is still high, copay savings cards can help make your prescription more affordable.
Free GoodRx coupons can also help you save on your prescription. For example, GoodRx can help you pay as little as $499 per month for Ozempic or Wegovy (semaglutide).
Over the last few years, medications like Ozempic (semaglutide) and Mounjaro (tirzepatide) have grown in popularity. These medications mimic one or two key gut hormones — glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) — which help regulate blood glucose (sugar), appetite, and more.
For many people, lack of insurance coverage, steep copays, and other factors can make these medications, known as GLP-1 or GIP/GLP-1 receptor agonists, difficult to access. And since these treatments are meant for long-term use, it’s essential to find ways to make them more affordable.
The good news is that there are resources available to help you save on your prescription — from GoodRx discounts and copay savings cards to patient assistance programs. Below is your complete guide for how to save on GLP-1 and GIP/GLP-1 receptor agonists.
The GLP-1 and GIP/GLP-1 receptor agonist graphics in this article are based on information from Pyrls, a professional drug information website and mobile application for healthcare professionals and trainees that specializes in pharmacotherapy charts and summaries.
How to save on GLP-1 and GIP/GLP-1 receptor agonists
The best way to save on GLP-1 and GIP/GLP-1 receptor agonists is by using your health insurance. But coverage can depend on your specific plan, health history, and other factors. If your cost is still high, or if you don’t have insurance, there are ways to make your prescription more affordable.
Save with GoodRx: Free GoodRx coupons can help you save on your prescription. For example, GoodRx can help you pay as little as $499 per month for Ozempic or Wegovy (semaglutide). Savings for other medications are also available.
Save with manufacturer copay cards: If you have commercial insurance, you may be eligible to save with a manufacturer copay card.
Save with patient assistance programs: If you’re uninsured or underinsured, you may qualify to get your medication at no cost through a patient assistance program.
Save with direct pharmacy options: You can access certain GLP-1s at a lower cost through LillyDirect or NovoCare Pharmacy.
Finding ways to make your prescription more affordable can help you start and stay consistent with your medication. Below, you’ll find medication-specific ways to save.
Good to know: The manufacturer of Mounjaro and Zepbound has a barcode scanning tool online to help you verify that the medication you're taking is legitimate. Using your phone's or computer's camera, scan the barcode on your product. The tool will tell you if it's authentic Mounjaro or Zepbound.
GLP-1 and GIP/GLP-1 receptor agonists for Type 2 diabetes
GLP-1 and GIP/GLP-1 receptor agonists were originally FDA approved to treat Type 2 diabetes. They’re very effective at lowering hemoglobin A1C (A1C or HbA1C) — average blood sugar levels over 3 months. They can also result in weight loss, which may be a treatment goal for some people. What’s more, some have proven cardiovascular and kidney benefits.
Most options for Type 2 diabetes are available as injections that are administered weekly, daily, or twice daily. There’s also one oral option. Which one you’re prescribed can depend on factors such as your treatment goals, health history, and preferences.
Medication | Description | How to save |
|---|---|---|
Ozempic (semaglutide)*^ | Once-weekly injection for adults | As low as $499 with a free GoodRx discount As low as $25 for a 1-, 2-, or 3-month supply with a manufacturer copay card Get Ozempic delivered to your home for $499 through NovoCare Pharmacy |
Rybelsus (semaglutide)* | Once-daily tablet for adults | As low as $984.58 with a free GoodRx discount As low as $10 for a 1-, 2-, or 3-month supply with a manufacturer copay card |
Trulicity (dulaglutide)* | Once-weekly injection for adults and children ages 10 and older | As low as $1019.99 with a free GoodRx discount As low as $25 for a 1-, 2-, or 3-month supply with a manufacturer copay card PAP for Trulicity (currently only available if you’re already enrolled or re-enrolling, with some exceptions) |
Mounjaro (tirzepatide) | Once-weekly injection for adults | As low as $1065.15 with a free GoodRx discount As low as $25 for a 1- or 3-month supply with a manufacturer copay card |
Victoza (liraglutide)* | Once-daily injection for adults and children ages 10 and older | As low as $808.73 for brand-name Victoza with a free GoodRx discount As low as $238.50 for the authorized generic with a free GoodRx discount |
Bydureon BCise (exenatide) | Once-weekly injection for adults and children ages 10 and older | As low as $793.12 with a free GoodRx discount As low as $0 for a 1-month supply with a manufacturer copay card |
Byetta (exenatide) | Twice-daily injection for adults | As low as $861.35 with a free GoodRx discount As low as $350.43 for the generic version with a free GoodRx discount As low as $25 for a 1-month supply with a manufacturer copay card |
*Also approved to lower the risk of major adverse cardiovascular events (heart attack, stroke, or cardiovascular death) in certain adults.
Is Ozempic covered by insurance? The short answer: It depends. Learn more about how various insurance providers approach coverage for Ozempic.
Off-label coverage: Some GLP-1 receptor agonists are prescribed off-label for weight loss and other uses. Here’s what you should know about how insurance covers off-label prescriptions.
How much does Mounjaro cost? Here’s how much Mounjaro costs with and without insurance, plus ways to make your prescription more affordable.
^Also approved to lower the risk of major kidney disease-related health events in adults with Type 2 diabetes and chronic kidney disease.
GLP-1 and GIP/GLP-1 receptor agonists for weight management
Certain GLP-1 and GIP/GLP-1 receptor agonists are specifically approved to help certain people with and without diabetes manage their body weight.
In addition to weight loss, some of them also have proven cardiovascular benefits or are approved for obstructive sleep apnea or liver disease, among other potential uses. Which one you’re prescribed depends on your health history, risk factors, treatment goals, and other factors.
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Medication | Description | How to save |
|---|---|---|
Wegovy (semaglutide)*† | Once-weekly injection for adults and adolescents ages 12 and older | As low as $499 with a free GoodRx discount As low as $0 for a 1-month supply with a manufacturer copay card As low as $499 for a 1-month supply if you’re uninsured or paying cash for Wegovy Get Wegovy delivered to your home for $499 through NovoCare Pharmacy |
Zepbound (tirzepatide)^ | Once-weekly injection for adults | As low as $1071.17 with a free GoodRx discount As low as $25 for a 1- or 3- month supply with a manufacturer copay card For single-dose vials, pay $349 (2.5 mg) and $499 (5 mg) per month through LillyDirect. Higher-strength vials also have savings opportunities through the Zepbound Self Pay Journey Program |
Saxenda (liraglutide) | Once-daily injection for adults and adolescents ages 12 and older | As low as $1389.64 for brand-name Saxenda with a free GoodRx discount As low as $372.45 for the generic version with a free GoodRx discount |
*Also approved to lower the risk of major adverse cardiovascular events (heart attack, stroke, or cardiovascular death) in certain adults
^Also approved for moderate-to-severe obstructive sleep apnea
†Also approved for adults with metabolic dysfunction-associated steatohepatitis (MASH) who have moderate to advanced liver scarring (fibrosis), but not cirrhosis, along with a reduced-calorie diet and increased physical activity
The bottom line
There are many ways to save on glucagon-like peptide-1 (GLP-1) receptor agonists like Ozempic (semaglutide) and Trulicity (dulaglutide). This is also the case for glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonists like Zepbound (tirzepatide) and Mounjaro (tirzepatide).
The best way to save on GLP-1 and GIP/GLP-1 agonists is by using your health insurance. But it’s possible that these medications aren’t covered, or that your cost is still high. Manufacturer copay cards and patient assistance programs can help make your prescription more affordable. GoodRx can also help you save money on your prescription.
Why trust our experts?
References
AstraZeneca. (n.d.). For commercially insured patients.
Business Wire. (2025). GoodRx announces collaboration with Novo Nordisk to expand access to Ozempic® and Wegovy® for $499-per-month.
Lilly Cares Foundation. (n.d.). Available medications.
Lilly Direct. (n.d.). Authentic Zepbound shipped directly to you.
NovoCare. (n.d.). Get Wegovy savings and WeGoTogether support.
NovoCare. (n.d.). NovoCare Pharmacy.
NovoCare. (n.d.). Patient assistance program.
