ACL inhibitors are used to reduce the risk of heart attack in people who cannot take a statin. They can also help lower LDL cholesterol levels. ACL inhibitors work by blocking the enzyme adenosine triphosphate-citrate lyase, which helps to reduce the production of cholesterol in your liver. These medications are typically available in oral form. An example include bempedoic acid (Nexletol). You can take these medications as prescribed to help manage your cholesterol levels and reduce your risk of heart-related issues.