The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Schizophrenia
- Sleepiness (24%)
- Nausea (9%)
- Dry mouth (6%)
- Dizziness (5%)
Bipolar depression
- Headache (14%)
- Sleepiness (13%)
- Dizziness (8%)
- Nausea (8%)
- Dry mouth (5%)
Depression
- Headache (19%)
- Dizziness (17%)
- Dry mouth (13%)
- Sleepiness (12%)
- Nausea (9%)
- Fatigue (8%)
- Diarrhea (5%)
Less Common Side Effects
- Vomiting
- Poor appetite
- Stomach pain
- Vertigo
- Trouble sleeping
Caplyta serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Neuroleptic malignant syndrome (NMS): high fever, sweating, confusion, stiffness, blood pressure instability
- Stroke: trouble speaking, trouble walking, sudden confusion, weakness in the face, arm, or leg
- Extremely high blood sugar levels: feeling very hungry or thirsty, urinating more often, fruity-smelling breath
- Uncontrolled muscle movements: involuntarily sticking out your tongue, puffing out your cheeks, puckering your mouth, lip smacking, chewing, foot tapping
- Serious infections: fever, weakness, tiredness, sore throat, cough, difficulty breathing
- Seizures
- Trouble swallowing
- Suicidal thoughts and behaviors
Source: Prescribing Information
The following Caplyta side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- High blood sugar (hyperglycemia)—increased thirst or amount of urine, unusual weakness or fatigue, blurry vision
- High fever, stiff muscles, increased sweating, fast or irregular heartbeat, and confusion, which may be signs of neuroleptic malignant syndrome
- Infection—fever, chills, cough, or sore throat
- Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
- Pain or trouble swallowing
- Seizures
- Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision
- Thoughts of suicide or self-harm, worsening mood, feelings of depression
- Uncontrolled and repetitive body movements, muscle stiffness or spasms, tremors or shaking, loss of balance or coordination, restlessness, shuffling walk, which may be signs of extrapyramidal symptoms (EPS)
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Diarrhea
- Dizziness
- Drowsiness
- Dry mouth
- Headache
- Nausea
- Weight gain
