Buspirone tablets help manage and relieve anxiety in adults. It belongs to a drug class called anxiolytics (or anti-anxiety medications). The tablets are taken by mouth, typically twice daily. Common side effects are dizziness, nausea, headache, and nervousness. Buspirone isn't a controlled substance. The brand name Buspar is no longer available, but you can get the generic buspirone tablets.
Buspirone is an anti-anxiety medication. It's unclear how the medication works. But it's thought to manage serotonin activity in the brain. Serotonin is a chemical in the brain that helps regulate mood.
| Common Brands | Buspar |
|---|---|
| Drug Class | Antianxiety |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | Lower-cost generic available |
| Availability | Prescription only |
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Contact your healthcare provider immediately if you experience any of the following.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Rare
confusion
fast or pounding heartbeat
incoordination
mental depression
muscle weakness
numbness, tingling, pain, or weakness in the hands or feet
skin rash or hives
stiffness of the arms or legs
uncontrolled movements of the body
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Dizziness or lightheadedness especially when getting up from a sitting or lying position suddenly
drowsiness (severe)
loss of consciousness
nausea or vomiting
stomach upset
very small pupils of the eyes
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Restlessness, nervousness, or unusual excitement
Less common or rare
Blurred vision
clamminess or sweating
decreased concentration
drowsiness
dryness of the mouth
muscle pain, spasms, cramps, or stiffness
ringing in the ears
trouble with sleeping, nightmares, or vivid dreams
unusual tiredness or weakness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Buspirone can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Buspirone can affect the serotonin levels in your brain. Because of this, it has a risk of serotonin syndrome. This is a rare but serious condition that happens when there's too much serotonin in the brain.
The risk is higher if you also take other medications that raise serotonin levels. They can include some antidepressants, migraine medications called triptans, and certain opioids. Tell your care team about all the medications and over-the-counter products you take so they can check your risk.
Watch for signs like a fever, fast heartbeat, sweating, muscle stiffness or spasms, or confusion. These can be signs of serotonin syndrome. If this happens while you're taking buspirone, get medical help right away.
Buspirone can make some people feel more sleepy. It can also make it harder to focus or react quickly. Not everyone has these side effects, and they can be hard to predict. Because of this, it's important to be aware that they can happen. Avoid driving, using machines, and doing anything that you need to be alert for until you know how buspirone affects you.
Don't take buspirone with a monoamine oxidase inhibitor (MAOI), like selegiline. Taking them together can cause very high blood pressure. It can also raise your risk of serotonin syndrome.
If you need to take both, wait at least 14 days after stopping one before starting the other. This gives your body time to clear the medication from your system.
Tell your prescriber and pharmacist about all the medications you take. They can make recommendations on how to take your medications to help keep you safe.
Buspirone works differently from other anxiety medications like benzodiazepines. Because of this, buspirone won't help prevent withdrawal symptoms if you stop a benzodiazepine too quickly.
If you're switching from a benzodiazepine to buspirone, work closely with your prescriber. They'll slowly lower your benzodiazepine dose over time. This helps lower the risk of withdrawal. Tell your care team if you have withdrawal symptoms, like nausea, vomiting, diarrhea, and headache, after stopping the benzodiazepine.
Tablet| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 5mg | 60 tablets | $9.00 | $0.15 |
| 10mg | 60 tablets | $9.00 | $0.15 |
| 15mg | 60 tablets | $16.48 | $0.27 |
| 30mg | 60 tablets | $20.64 | $0.34 |
| 7.5mg | 60 tablets | $20.73 | $0.35 |
The typical starting dose is 7.5 mg by mouth twice daily. Your prescriber might raise your dose every few days depending on how it works for you.
Most people take 20 mg to 30 mg daily. The maximum dose is 60 mg daily.
Your dose might differ if you take medications that interact with buspirone.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Buspirone will not be safe for you to take.
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No. Buspirone isn't classified as a controlled substance. Studies show that it has a low risk of dependence and withdrawal. This is unlike other common anxiety medications like benzodiazepines. Talk to your prescriber if you're concerned about this issue. They can help find an anxiety medication that's right for you.
No. Buspirone isn't an SSRI, or a selective serotonin reuptake inhibitor. Instead, it's classified as a general anti-anxiety medication. Buspirone and certain SSRIs can help with anxiety. They both work by affecting a brain chemical called serotonin to help manage anxiety. But they do so in very different ways. Your prescriber or care team can help explain which option is the best fit for your specific needs.
Weight gain isn't a common side effect of Buspirone. It's rare for people to report weight gain after taking this medication. Even so, the weight gain is likely minimal. And it's not clear whether any weight gain can be linked directly to Buspirone. If you notice weight gain while taking Buspirone and are worried, talk to your primary care provider.
It's possible. Some people might feel sleepy or tired as side effects of Buspirone. Other people might also have trouble sleeping (insomnia). Keep in mind that anxiety itself can make you feel tired or have sleep problems. It can be hard to predict how Buspirone makes you feel. So, avoid driving or doing anything that you need to be alert for until you know how this medication affects you. Talk to your prescriber if you feel very sleepy that it's making it hard for you to go about your day. They can talk to you about your options.
It can take about 2 to 4 weeks to notice improvements in your anxiety symptoms after starting Buspirone. Keep in mind that it can take some time for your prescriber to adjust your dose and find what works best for you. Try to be patient and keep taking Buspirone every day as prescribed, even if you don't feel better right away. Talk to your prescriber if you're not sure it's working.
For most people, it takes about 15 hours for Buspirone to fully leave your body after you take it. This is based on its half-life, which is how long it takes for half of the medication to get out of your system. It can take longer for Buspirone to leave your system if you have liver or kidney problems. This is because the liver and kidneys help get rid of the medication from your body. Ask your prescriber if you have questions about how long Buspirone stays in your system.
It’s generally best to avoid drinking alcohol while you’re taking Buspirone. Alcohol can make side effects like drowsiness or nausea worse. Mixing the two can be especially risky if you’re driving or using machinery. Alcohol can also make your anxiety worse. Talk to your care team about how much you usually drink. They can talk to you about how to take Buspirone safely and healthy ways to cope with anxiety.
If you're pregnant or planning to become pregnant, let your care team know. They can explain the risks and benefits of treatment. We don't know for sure if Buspirone is safe during pregnancy. Animal studies suggest there's low risk, but this might not be the same in people. Your prescriber will likely only recommend taking it during pregnancy if the benefits are greater than the risks to your unborn baby. They can also talk with you about other ways to manage your anxiety during pregnancy.
