Zyban (bupropion extended-release) is an atypical antidepressant used as an aid in smoking cessation. Bupropion is also the active ingredient in Wellbutrin, which is used to treat depression. Both Zyban and Wellbutrin are available as generic bupropion, but may not be substituted for each other. Get Bupropion (Zyban) for as low as $12.78, which is 79% off the average retail price of $61.97 for the most common version, by using a GoodRx coupon.
