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Bumetanide Coupon - Bumetanide 1mg tablet

bumetanide

Generic Bumex
Used for Edema, Heart Failure
Used for Edema, Heart Failure

Bumetanide (Bumex) is a strong diuretic (water pill) that works well at removing extra fluid from your body. It's primarily used to ease swelling for people with heart failure, liver problems, or kidney disease. Bumetanide (Bumex) is taken by mouth, typically once daily, though some people might need to take it every other day. Some side effects of this medication include muscle cramps, dizziness, and low electrolytes levels (e.g., low potassium levels, low sodium levels). Bumetanide (Bumex) is available as a brand name and generic tablet.

Reviewed by:
reviewer
Allison Gourley, PharmD
reviewer
Connie Zheng, PharmD
Last reviewed on April 30, 2023
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesLatest newsImagesReferencesPricesMedicare
basics-icon

What is Bumetanide (Bumex)?

What is Bumetanide (Bumex) used for?

  • Swelling (edema) due to congestive heart failure, liver problems, or kidney problems

How Bumetanide (Bumex) works

Bumetanide (Bumex) is a loop diuretic (water pill) that makes you urinate more. It works in the kidneys to get rid of extra water and electrolytes (like sodium and potassium), which helps ease swelling.

When does Bumetanide (Bumex) start working?
Time passed since treatment started:
MINUTES
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsBumex
Drug ClassDiuretic (water pill)
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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What are the side effects of Bumetanide (Bumex)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Other Side Effects

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Severe dehydration: feeling thirsty, lightheadedness, dry mouth, dark colored urine, urinating less
  • Low levels of potassium in the blood: muscle weakness and spasms, tiredness, heart racing, constipation, tingling or numbness, nausea, vomiting, muscle pain, confusion
  • Stevens-Johnson Syndrome and toxic epidermal necrolysis: skin pain, fever, body aches, red rash, peeling skin, blisters, sores
When do Bumetanide (Bumex) possible side effects begin and end?
Time passed since treatment started:
MINUTES
HOURS
DAYS
WEEKS
MONTHS
Dizziness
Muscle cramps
Changes in electrolyte levels
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

More on Bumetanide (Bumex) side effects

bumex: side effects bumex

7 Bumex Side Effects to Know About

Written by Rosanna Sutherby, PharmD

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal pain

blurred vision

confusion

decreased urine output

dizziness

drowsiness

dry mouth

fast or irregular heartbeat

flushed, dry skin

fruit-like breath odor

headache

increased hunger

increased thirst

increased urination

irritability

joint pain, stiffness, or swelling

loss of appetite

loss of mental alertness

lower back, side, or stomach pain

mood or mental changes

muscle pain or cramps

nausea or vomiting

numbness or tingling in the hands, feet, or lips

shortness of breath

sweating

swelling of face, hands, feet, ankles, or lower legs

troubled breathing

unexplained weight loss

unusual tiredness or weakness

weak pulse

Rare

Agitation

back pain

black, tarry stools

bleeding gums

blood in the urine or stools

chest pain

convulsions (seizures)

deep or fast breathing with dizziness

dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly

fever

hallucinations

hives

increase in heart rate

increased blood pressure

numbness of feet, hands, and around the mouth

pinpoint red spots on the skin

rapid breathing

stiff neck

sunken eyes

trembling, jerking of hands

unusual bleeding or bruising

weight gain

wrinkled skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Difficulty breathing

pain in chest, groin, or legs, especially the calves

severe, sudden headache

slurred speech

sudden loss of coordination

sudden, severe weakness or numbness in the arm or leg

sudden, unexplained shortness of breath

unusual drowsiness, dullness, or feeling of sluggishness

vision changes

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

Decreased interest in sexual intercourse

diarrhea

difficulty with moving

ear discomfort

feeling of constant movement of self or surroundings

inability to have or keep an erection

itching skin

loss in sexual ability, desire, drive, or performance

muscle or bone pain

muscle stiffness

nipple tenderness

pain, swelling, or redness in joints

rash

sensation of spinning

shorter than usual time to ejaculation of semen

trouble with hearing

upset stomach

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Bumetanide (Bumex)

thumbs-up

Pros

Works within an hour to get rid of extra fluid in your body

Typically taken once daily

A possible option for people who are allergic to furosemide (Lasix)

thumbs-down

Cons

Raises your risk for dehydration

Might need regular blood tests to check electrolytes and kidney health

Makes you urinate more often right after taking it

pharmacist-tips

Pharmacist tips for Bumetanide (Bumex)

pharmacist

  • Bumetanide (Bumex) usually makes you have to urinate more 30 to 60 minutes after taking the medication. This effect lasts 4 to 6 hours. Try to take bumetanide (Bumex) earlier in the day so that you don't have to get up to urinate in the middle of the night.

    • Bumetanide (Bumex) can cause lightheadedness and dizziness, especially during the first few days of therapy. To lower the chance of feeling dizzy, get up slowly from sitting or lying down. Avoid driving and doing tasks that require a lot of attention until you know how this medication affects you. If you feel like you're going to faint or pass out, let your provider know right away.

      • Your provider might ask that you to weigh yourself while you're taking bumetanide (Bumex). This can help them understand how well bumetanide (Bumex) is working to remove fluids from your body and whether or not they need to adjust your dose.

        • Since bumetanide (Bumex) gets rid of extra fluid from your body, sometimes this can lead to too much water and electrolytes, specifically potassium, in the blood being lost. Tell your provider right away if you feel weak, have muscle pain or cramps, dizziness, fast heartbeat, or vomiting. Your provider might ask you to take extra potassium if needed.

          • Please tell your provider right away if you experience vomiting, diarrhea, or fever. Also, let them know if you haven't been drinking fluids as often as usual during treatment. These factors can lead to dehydration, which raises the risk of serious kidney problems.

            faqs

            Frequently asked questions about Bumetanide (Bumex)

            How long does bumetanide (Bumex) stay in your system?
            How long the effects of bumetanide (Bumex) last can depend on your dose. At the typical doses of bumetanide (Bumex) 1 mg to 2 mg, you'll likely notice an urge to urinate more often starting about 30 minutes after you take the medication and continuing for about 4 hours afterwards. If you're taking a higher dose, the effects of bumetanide (Bumex) might last about 4 to 6 hours. Ask your provider if you've more questions about how long bumetanide (Bumex) stays in your system or its effects on your body.
            Does bumetanide (Bumex) lower blood pressure?
            Bumetanide (Bumex) isn't FDA-approved to help lower blood pressure. But clinical trials show that it can cause low blood pressure as a side effect, though this isn't very common (experienced by less than 1% of people). If you have high blood pressure, let your provider know. They might be able to recommend other water pills similar to bumetanide (Bumex) that are FDA-approved to lower blood pressure, such as furosemide (Lasix).
            Does bumetanide (Bumex) lower potassium levels?
            Yes, bumetanide (Bumex) can lower your potassium levels. This is because it lowers swelling by causing your kidneys to get rid of more fluids and electrolytes, including potassium. Low potassium levels can be dangerous, so your provider will most likely order blood work regularly for you while you're taking bumetanide (Bumex) to make sure your blood potassium levels are in a safe range. Let your provider know right away if you experience symptoms of low potassium levels, such as muscle weakness, muscle twitching, and numbness. They'll likely need to check your potassium levels or make changes to your medications.
            What's the difference between bumetanide (Bumex) and furosemide (Lasix)?
            Bumetanide (Bumex) and furosemide (Lasix) are both water pills called loop diuretics and can cause similar side effects, such as headaches or dizziness. The main difference is that furosemide (Lasix) is FDA-approved to lower blood pressure, but bumetanide (Bumex) isn't. So furosemide (Lasix) might be a better choice for you if you've high blood pressure in addition to swelling. But if you already have low blood pressure, then your provider might pick bumetanide (Bumex) to avoid having your blood pressure drop too low. Another thing to note is that even though bumetanide (Bumex) and furosemide (Lasix) are similar medications, study shows that people who are allergic to furosemide (Lasix) can most likely take bumetanide (Bumex) without the same reactions. Let your provider know if you've more questions about the differences between bumetanide (Bumex) and furosemide (Lasix).
            Is bumetanide (Bumex) stronger than Lasix (furosemide)?
            Bumetanide (Bumex) and furosemide (Lasix) are commonly prescribed loop diuretics (water pills) to ease swelling. Bumetanide (Bumex) is considered to be "stronger" than furosemide (Lasix) when you compare them milligram to milligram. When comparing oral tablets, 1 mg of bumetanide (Bumex) works about as well as 40 mg of furosemide (Lasix).
            Is bumetanide (Bumex) hard on the kidneys?
            Talk with your provider if you have kidney problems. While bumetanide (Bumex) can be taken by some people with kidney problems to relieve swelling, it might not be a good option for everyone. Because bumetanide (Bumex) works by causing you to urinate more, you're at risk for becoming dehydrated or losing too much electrolytes. If you already have kidney problems, these side effects can further harm your kidneys. Your provider will likely want to check your fluid and electrolyte level regularly if you do have any kidney conditions.
            Does bumetanide (Bumex) contain sulfa?
            Yes, bumetanide (Bumex) does contain sulfa. If you've had an allergic reaction to any sulfa antibiotics in the past, let your provider know. They'll want to learn more about the kind of symptoms you've experienced and whether or not you've had any trouble breathing or serious rash. If your past allergic reaction was mild, you might still be able to take bumetanide (Bumex) without any serious problems.
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            What are the risks and warnings for Bumetanide (Bumex)?

            Bumetanide (Bumex) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

            risk-warning

            Not enough fluids or electrolytes in your body

            • Risk factors: Age 65 or older | Taking higher doses of bumetanide (Bumex) | Liver disease like cirrhosis | Recent diarrhea | Not enough salt or electrolytes in your diet | Taking other diuretics (water pills) | History of certain irregular heart rhythms

              Bumetanide (Bumex) is a very strong diuretic (water pill). Taking too much of it can lead to dehydration and low electrolyte levels, which can be life-threatening. Low potassium levels and low chloride levels are most common, but you can also have low sodium, calcium, and magnesium levels. It's important to take bumetanide (Bumex) exactly as prescribed. Your provider might order blood work to check your electrolyte levels from time to time. Ask your provider how much water you should drink daily to stay hydrated. Get medical attention if you notice dry mouth, thirst, weakness, drowsiness, muscle cramps, fast heart rate, or unusually low amounts of urine after taking bumetanide (Bumex).

              risk-warning

              Hearing problems

              • Risk factors: Current kidney problems | Taking higher doses of bumetanide (Bumex) | Other medications that cause hearing problems

                Bumetanide (Bumex) was shown to cause hearing loss at very high doses in some animal studies. Though possible, the likelihood of this side effect in people is low, especially at the recommended dosing range for oral tablets. The risk of hearing loss is higher for people who receive high doses of intravenous bumetanide (Bumex). Take bumetanide (Bumex) exactly as prescribed and make sure to have lab tests done regularly. Let your healthcare provider know right away if you notice any new problems with your hearing.

                risk-warning

                Allergic reaction

                • Risk factors: History of severe sulfa allergy

                  People with severe allergies to other sulfa-containing medications might experience similar reactions with bumetanide (Bumex). Make sure your healthcare provider and pharmacist know about all of your drug allergies, especially if they are severe. Stop taking bumetanide (Bumex) and call your provider if you notice a rash, hives, or other signs of an allergic reaction.

                  risk-warning

                  Low platelet count

                  In some rare cases, people have had low platelet counts after taking bumetanide (Bumex). Your healthcare provider will watch for this on regular blood tests, but call your provider if you notice unusual or unexplained bleeding or bruises on your skin.

                  dosage

                  Bumetanide (Bumex) dosage forms

                  The average cost for 30 tablets of 1mg of Bumetanide (Bumex) is $14.11 with a free GoodRx coupon. This is 55.91% off the average retail price of $31.99.
                  tablet
                  Tablet
                  DosageQuantityPrice as low asPrice per unit
                  0.5mg90 tablets$21.35$0.24
                  1mg30 tablets$14.11$0.47
                  2mg60 tablets$29.24$0.49

                  Typical dosing for Bumetanide (Bumex)

                  The usual dose of bumetanide (Bumex) is 0.5 mg to 2 mg taken by mouth once a day. Your provider will adjust your dose as needed to keep your swelling under control. Depending on your condition, your provider might ask you to take bumetanide (Bumex) every other day or every 2 days. The maximum dose is 10 mg a day.

                  interactions

                  Interactions between Bumetanide (Bumex) and other drugs

                  Bumetanide (Bumex) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Bumetanide (Bumex). Please note that only the generic name of each medication is listed below.

                  Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                  Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                  Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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                  contraindications-icon

                  Bumetanide (Bumex) contraindications

                  Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Bumetanide (Bumex) will not be safe for you to take.
                  alternatives

                  What are alternatives to Bumetanide (Bumex)?

                  There are a number of medications that your doctor can prescribe in place of Bumetanide (Bumex). Compare a few possible alternatives below.
                  Bumetanide (Bumex)
                  Used for:

                  • Swelling (edema) due to congestive heart failure, liver problems, or kidney problems

                  $14.11 Lowest GoodRx priceView Prices
                  Furosemide (Lasix)
                  Used for:
                  $1.80 Lowest GoodRx priceView Prices
                  Torsemide
                  Used for:

                  • Swelling due to heart failure or kidney disease

                  • Swelling due to liver disease (taken with other medications) - generic bumetanide (Bumex) only

                  • High blood pressure - generic bumetanide (Bumex) only

                  $9.00 Lowest GoodRx priceView Prices
                  latest news

                  What is the latest news about Bumetanide (Bumex)?

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                  7 Bumex Side Effects to Know About

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                  Loop diuretics treat hypertension and edema from heart failure or kidney disease. Learn about loop diuretics’ mechanism of action for fluid overload conditions.

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                  images

                  Bumetanide (Bumex) images

                  Yellow Round E 129 - Bumetanide 1mg Tablet
                  This medicine is Yellow, Round, Scored Tablet Imprinted With "E 129".Yellow Round E 129 - Bumetanide 1mg Tablet
                  Yellow Oval 370 And Mylan - Bumetanide 1mg Tablet
                  This medicine is Yellow, Oval, Notched Tablet Imprinted With "370" And "Mylan".Yellow Oval 370 And Mylan - Bumetanide 1mg Tablet
                  Yellow Round U-S 41 And 1 - Bumetanide 1mg Tablet
                  This medicine is Yellow, Round, Scored Tablet Imprinted With "1" And "U-S 41".Yellow Round U-S 41 And 1 - Bumetanide 1mg Tablet
                  White Round 1 And Bum - Bumetanide 1mg Tablet
                  This medicine is White, Round, Scored Tablet Imprinted With "1" And "Bum".White Round 1 And Bum - Bumetanide 1mg Tablet
                  Yellow Oval Bumex 1 - Bumetanide 1mg Tablet
                  This medicine is Yellow, Oval Tablet Imprinted With "Bumex 1".Yellow Oval Bumex 1 - Bumetanide 1mg Tablet
                  White Round Ac 164 - Bumetanide 1mg Tablet
                  This medicine is White, Round, Scored Tablet Imprinted With "Ac 164".White Round Ac 164 - Bumetanide 1mg Tablet
                  White Round Ac 164 - Bumetanide 1mg Tablet
                  This medicine is White, Round, Scored Tablet Imprinted With "Ac 164".White Round Ac 164 - Bumetanide 1mg Tablet
                  Yellow Round B 1 - Bumetanide 1mg Tablet
                  This medicine is Yellow, Round Tablet Imprinted With "B 1".Yellow Round B 1 - Bumetanide 1mg Tablet
                  Yellow Round 5 26 - Bumetanide 1mg Tablet
                  This medicine is Yellow, Round, Scored Tablet Imprinted With "5 26".Yellow Round 5 26 - Bumetanide 1mg Tablet
                  White Round Ac 41 - Bumetanide 1mg Tablet
                  This medicine is White, Round, Scored Tablet Imprinted With "Ac 41".White Round Ac 41 - Bumetanide 1mg Tablet
                  Yellow Round Logo 32 - Bumetanide 1mg Tablet
                  This medicine is Yellow, Round Tablet Imprinted With "Logo 32".Yellow Round Logo 32 - Bumetanide 1mg Tablet

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                  References

                  Best studies we found

                  National Organization for Rare Disorders. (2011). Hepatic encephalopathy.

                  Ng, T. M. H., et al. (2013). Comparison of bumetanide- and metolazone-based diuretic regimens to furosemide in acute heart failure. Journal of Cardiovascular Pharmacology and Therapeutics.

                  Shisler, D., et al. (2014). Syndrome of severe pain associated with a continuous bumetanide infusion. International Journal of Cardiology.

                  View All References (2)

                  Testani, J. M., et al. (2014). Loop diuretic efficiency: A metric of diuretic responsiveness with prognostic importance in acute decompensated heart failure. Circulation: Heart Failure.

                  Upsher-Smith Laboratories, LLC. (2023). BUMETANIDE tablet [package insert]. DailyMed.

                  GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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