- Tamiflu (oseltamivir) has activity against influenza A and B unlike amantadine and rimantadine (Flumadine), which only have activity against influenza A.
- Tamiflu reduces the time of improvement by 1.3 days (30%) compared to patients receiving placebo.
- For it to work, you must begin Tamiflu within 48 hours of symptom onset.
- Tamiflu is not considered a substitute for annual influenza virus vaccination and trust me, it’s not.
- Tamiflu works by inhibiting the enzyme (viral neuraminidase) which promotes the spread of a virus in the respiratory tract.
- Tamiflu-resistant strains of the virus have shown up during some flu seasons and in some geographic locations.
- The most frequent side effect from Tamiflu is nausea and vomiting. In adults, nausea was reported in 8% of those taking Tamiflu.
- Tamiflu will not work for colds, or other viral infections.
- In December of 2012, the US Food and Drug Administration (FDA) approved the use of Tamiflu for the treatment of influenza in infants aged 2 weeks and older.
- There are no known interactions between Tamiflu and any other medication so it is fine to take along with other meds.
Tamiflu is covered by many insurance plans as a Tier 2 drug, meaning a moderately high copay. A course of the 75 mg twice daily dose (10 capsules) will run about $110 – $120 if you are paying out of pocket.