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Bleomycin

Bleomycin Side Effects

Allison Baxley, PharmD, BCOPCydnee Ng, PharmD
Reviewed by Allison Baxley, PharmD, BCOP, Cydnee Ng, PharmD
Last reviewed on December 1, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Trouble breathing
  • Lower appetite
  • Weight loss
  • Tiredness

Less Common Side Effects

  • Vomiting
  • Skin redness or tenderness
  • Skin color changes
  • Itchy skin
  • Rash
  • Fever
  • Chills
  • Hair loss
  • Confusion

Bleomycin serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious lung toxicity: trouble breathing, cough, chest tightness
  • Serious reaction to the medication: fever, chills, trouble breathing, confusion, lightheadedness

Source: DailyMed

The following Bleomycin side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These delayed effects may include certain types of cancer, such as leukemia. Discuss these possible effects with your doctor.

Check with your doctor immediately if any of the following side effects occur:

More common

Fever and chills (occurring within 3 to 6 hours after a dose)

Less common

Confusion

faintness

wheezing

Rare

Chest pain (sudden severe)

weakness in arms or legs (sudden)

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Cough

shortness of breath

sores in mouth and on lips

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Darkening or thickening of skin

dark stripes on skin

itching of skin

skin rash or colored bumps on fingertips, elbows, or palms

skin redness or tenderness

swelling of fingers

vomiting and loss of appetite

Less common

Changes in fingernails or toenails

weight loss

Bleomycin may cause a temporary loss of hair in some people. After treatment has ended, normal hair growth should return, although it may take several months.

Side effects that affect your lungs (for example, cough and shortness of breath) may be more likely to occur if you smoke.

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

Cough

shortness of breath

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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