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Bicillin CR

Bicillin CR Dosage

Michelle Nguyen, PharmDCydnee Ng, PharmD
Reviewed by Michelle Nguyen, PharmD, Cydnee Ng, PharmD
Last reviewed on April 23, 2025

The average cost for 1 package of 10 syringes of 1.2 million units per 2ml of Bicillin CR is $2,404.28 with a free GoodRx coupon. This is 19.35% off the average retail price of $2,981.25.

packagePackage

Dosage

Quantity

Price as low as

Price per unit

10 syringes of 1.2 million units per 2ml

1 package

$2,404.28

$2,404.28

10 pediatric syringes of 1.2 million units per 2ml

1 package

$2,404.28

$2,404.28

Typical dosage for Bicillin CR

This medication is given as an injection into the muscle, usually in the buttock. For babies and young children, the thigh muscle might be a better spot. It's given by a healthcare professional (HCP) at a medical office.

Bicillin CR

  • Each injection contains 600,000 units of penicillin G benzathine and 600,000 units of penicillin G procaine.

  • Strep throat, upper respiratory tract infection, skin or soft tissue infection, scarlet fever, or erysipelas: Most times, the HCP will give the dose using multiple injection sites during the same visit. Another option is to split the dose in half and give it to you on day 1 and day 3.

    • Adults and children over 60 lbs: The typical dose is 2,400,000 units injected into the muscle once as a single dose.
    • Children weighing 30 lbs to 60 lbs: The typical dose is 900,000 to 1,200,000 units injected into the muscle once as a single dose.
    • Children under 30 lbs: The typical dose is 600,000 units injected into the muscle once as a single dose.
  • Pneumonia or ear infection

    • Adults: The typical dose is 1,200,000 units injected into the muscle, repeated every 2 or 3 days until your temperature is normal for 48 hours (2 days).
    • Children: The typical dose is 600,000 units injected into the muscle, repeated every 2 or 3 days until your child's temperature becomes normal for 48 hours (2 days).

Bicillin C-R 900/300 (for children only)

  • Each injection contains 900,000 units of penicillin G benzathine and 300,000 units of penicillin G procaine.

  • Strep throat, upper respiratory tract infection, skin or soft tissue infection, scarlet fever, or erysipelas: The typical dose is 1 injection into the muscle once as a single dose.

  • Pneumonia or ear infection: The typical dose is 1 injection into the muscle, repeated every 2 or 3 days until your child's temperature is normal for 48 hours (2 days).

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Why trust our experts?

Michelle Nguyen, PharmD, has been a clinical pharmacist for 6 years (and counting). She has a diverse skill set within managed care pharmacy, specifically in the settings of a medical group, pharmacy benefit manager (PBM), and health plan.
Cydnee Ng, PharmD
Reviewed by:
Cydnee Ng, PharmD
Cydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.

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