Besivance is a prescription eye drop used to treat bacterial pink eye in adults and children 1 year of age and older. It belongs to the fluoroquinolone antibiotic class. The dosage is typically 1 drop three times per day for 7 days to treat the eye infection. Currently it's available only as a brand-name medication as a generic is not yet available. Side effects aren't common, but include eye redness.
Bacterial conjunctivitis (pink eye) in people ages 1 year and older
Besivance (besifloxacin) is a fluoroquinolone antibiotic. It works by blocking certain proteins that bacteria use to grow, repair their genetic material (DNA), and survive. By blocking this process, Besivance (besifloxacin) kills bacteria.
Source: DailyMed
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Headache
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Applied directly to the eye to target the infection
Side effects aren't common and are usually mild
Can be used in children as young as 1 year old
Can cause temporary eye redness or irritation
Can take days before you get symptom relief
No lower-cost generic is available
Make sure to use Besivance (besifloxacin) for the full amount of time your prescriber told you to, even if your eye starts to get better. Stopping the antibiotic eye drop too soon can cause your infection to come back and be harder to treat.
Wash your hands before and after putting Besivance (besifloxacin) drops in your eyes. Don't let the dropper tip touch your eye, fingers, or any other surface. This will help to avoid contaminating the solution.
If you need to use other eye drop medications in addition to Besivance (besifloxacin), wait 5 minutes between using each drop to give your eyes time to fully absorb each medication.
In general, it's best to avoid wearing contact lenses if you have an eye infection to prevent worsening the infection or further irritating your eye. Your prescriber will tell you when it's safe to wear contacts again.
Store the Besivance (besifloxacin) bottle at room temperature. Don't put it in the refrigerator or freezer.
How to use Besivance (besifloxacin):
Shake the bottle once to mix the medication.
Tilt your head backward and look up. Gently pull your lower eyelid down to form a small pocket. Then, squeeze one drop of medication into this pocket.
Close your eye while pressing a finger against the inside corner of your eye for about one minute to help keep the medication in your eye.
Besivance (besifloxacin) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Besivance (besifloxacin) is an eye drop medication that should only be placed on the surface of the eye. The medication shouldn't be injected into the eye or used in other places on your body, unless a healthcare provider specifically said it was safe to do so.
Risk factor: Using Besivance (besifloxacin) longer than prescribed
Using Besivance (besifloxacin) for too long can allow any bacteria, fungi, or other germs that the medication can't get rid of to infect the eye. Contact your primary care provider for follow-up if your eye infection isn't improving. You might need additional testing and treatment.
| Dosage | Quantity | Price as low as | Price per unit | 
|---|---|---|---|
| 5ml of 0.6% | 1 eye dropper | $239.73 | $239.73 | 
The typical dose is to put 1 drop in the affected eye(s) 3 times per day (4 to 12 hours apart) for 7 days.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
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American Academy of Allergy, Asthma & Immunology. (2024). Tips for administering eye drops.
American Optometric Association. (n.d.). Conjunctivitis (pink eye).
Bausch & Lomb Incorporated. (2022). Besivance- besifloxacin suspension [package insert]. DailyMed.
McDonald, M. B., et al. (2009). Efficacy and safety of besifloxacin ophthalmic suspension 0.6% compared with moxifloxacin ophthalmic solution 0.5% for treating bacterial conjunctivitis. Ophthalmology.
SafeMedication. (n.d.). How to use eye drops.
Valentini, C., et al. (2021). Price differences between otic and ophthalmic drops. Otology & Neurotology.
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