Head-to-head comparisons of medication uses, side effects, warnings, and more.
Polytrim (polymyxin B / trimethoprim)
Besivance (besifloxacin)
Polytrim (polymyxin B / trimethoprim)
Besivance (besifloxacin)
Summary of Polytrim vs. Besivance
Summary for Antibiotic
Prescription only
Polytrim (polymyxin B / trimethoprim) is a combination antibiotic eye drop. It's used to treat mild-to-moderate bacterial eye infections, such as pink eye, in adults and children ages 2 months and older. The typical dose is 1 drop applied directly in the eye(s) every 3 hours for 7 to 10 days. Some of the more common side effects of this eye drop include symptoms of eye irritation, such as redness, stinging, and itching. Polytrim (polymyxin B / trimethoprim) is available as a lower-cost generic.
Summary for Fluoroquinolone antibiotic
Prescription only
Besivance is a prescription eye drop used to treat bacterial pink eye in adults and children 1 year of age and older. It belongs to the fluoroquinolone antibiotic class. The dosage is typically 1 drop three times per day for 7 days to treat the eye infection. Currently it's available only as a brand-name medication as a generic is not yet available. Side effects aren't common, but include eye redness.
Indications of Polytrim vs. Besivance
Indications for
•Mild-to-moderate infections on the eye and eyelid
Indications for
•Bacterial conjunctivitis (pink eye) in people ages 1 year and older
Pros and Cons of Polytrim vs. Besivance
Pros and Const for Antibiotic
Pros
•Can treat a variety of eye infections in adults and children
•Available as a lower-cost generic
•Applied directly on the eyes, so it has less side effects than oral antibiotics
Cons
•Has to be used every 3 hours for at least a week
•Can cause temporary eye irritation after applying
•Can make your eyes more sensitive to light
Pros and Const for Fluoroquinolone antibiotic
Pros
•Applied directly to the eye to target the infection