What is the downside to Humira?

Humira works by intentionally lowering your immune response. At the same time, your immune system also has a weaker response to germs that make you sick. So you may be more likely to catch a bug or the latest cold that’s going around. Skin or urinary tract infections are possible, too. More serious infections can also happen. Because of this, the FDA requires products like Humira to have a boxed warning — their most serious medication warning — about their serious infection risk. View original source