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Zolmitriptan

Zolmitriptan Side Effects

Cydnee Ng, PharmDAshley Wong, PharmD
Reviewed by Cydnee Ng, PharmD, Ashley Wong, PharmD
Last reviewed on May 18, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Tablets and orally disintegrating tablets

  • Nausea (up to 9%)
  • Dizziness (up to 8%)
  • Pins and needles feeling in the arms or legs (up to 7%)
  • Neck, throat, or jaw pain, tightness, or pressure (up to 7%)
  • Sleepiness (up to 6%)
  • Feeling warm or cold (up to 6%)
  • Body weakness (up to 5%)
  • Dry mouth (up to 5%)
  • Chest pain, tightness, pressure, or heaviness (up to 3%)

Nasal spray

  • Unusual taste (up to 17%)
  • Dizziness (6%)
  • Pins and needles feeling in your arms or legs (5%)
  • Throat pain (4%)
  • Feeling warm (4%)
  • Dry mouth (3%)
  • Body weakness (3%)

Less Common Side Effects

Tablets and orally disintegrating tablets

  • Stomach upset
  • Feelings of heaviness in other parts of the body
  • Sweating

Nasal spray

  • Body weakness
  • Sleepiness
  • Nausea
  • Nasal discomfort
  • Higher sensitivity to touch, smell, taste, etc.

Zolmitriptan serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Heart attack: chest or arm pain, shortness of breath, cold sweat
  • Stroke: sudden weakness on one side of your body, headache, changes in your speech or vision, confusion
  • Serotonin syndrome: high fever, racing heart, hallucinations, sudden changes in thought or mood, movement problems
  • Allergic reaction: rash; hives; difficulty breathing or swallowing; swollen face, lips, mouth, tongue, or throat
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Source: DailyMed

The following Zolmitriptan side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Chest pain (severe)

heaviness, tightness, or pressure in the chest or neck

sensation of burning, warmth, heat, numbness, tightness, or tingling

Less common or rare

Abdominal or stomach pain (severe)

changes in facial skin color

cough or hoarseness

diarrhea

fast or irregular heartbeat

fever or chills

hives, itching, or skin rash

itching

loss of appetite

lower back or side pain

nausea

painful or difficult urination

puffiness or swelling of the eyelids or around the eyes, face, or lips

tightness in the chest

trouble breathing

weakness

Rare

Blurred vision

confusion

difficulty swallowing

dizziness

fainting

frequent strong or increased urge to urinate

headache

increased volume of pale, dilute urine

nervousness

pounding in the ears

severe numbness, especially on one side of the face or body

slow heartbeat

unusual tiredness or weakness

Incidence not known

Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Lack or loss of strength

sleepiness or unusual drowsiness

warm or cold sensation

Less common

Dizziness or lightheadedness

dry mouth

feeling of constant movement of self or surroundings

sensation of spinning

Rare

Anxiety

crying

depersonalization

depression

dysphoria

euphoria

hyperventilation

irritability

loss of memory

paranoia

problems with memory

quick to react or overreact emotionally

rapidly changing moods

redness of the skin

seeing, hearing, or feeling things that are not there

shaking

trouble sleeping

welts

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Cydnee Ng, PharmD
Reviewed by:
Cydnee Ng, PharmD
Cydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.
Ashley Wong, PharmD, is a licensed pharmacist in California. She has over 6 years of experience providing drug information.

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