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Diet and Nutrition

MSG Probably Isn’t as Harmful as You Think It Is

People have blamed many health issues on MSG, so here's what the science says.

Lauren Smith, MAMera Goodman, MD, FAAP
Written by Lauren Smith, MA | Reviewed by Mera Goodman, MD, FAAP
Updated on November 11, 2025
Reviewed by Mera Goodman, MD, FAAP | November 11, 2025

The controversy over MSG, or monosodium L-glutamate, began in the 1960s. People complained that they had headaches, sweating, and more after eating food with MSG. 

This food additive has a fascinating (and problematic) history, and after years of being feared, studies are showing the critiques against MSG may be unfounded.

References

Freeman, M. (2006). Reconsidering the effects of monosodium glutamate: A literature review. Journal of the American Academy of Nurse Practitioners.

Henry-Unaeze, H. N. (2017). Update on food safety of monosodium l-glutamate (MSG). Pathophysiology.

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Lauren Smith, MA
Written by:
Lauren Smith, MA
Lauren Smith, MA, has worked in health journalism since 2017. Before joining GoodRx, she was the senior health editor and writer for HealthiNation.
Mera Goodman, MD, FAAP, is a board-certified pediatrician. Prior to practicing medicine, she worked as a management consultant.

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