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Votrient
Specialty Drug

Pazopanib

Votrient is part of the Kinase Inhibitors class and treats Soft Tissue Sarcoma and Renal Cancer. Kinase inhibitors are used to treat cancers such as leukemia, breast cancer, melanoma, lung cancer, and renal cancer. They are also used in the treatment of rheumatoid arthritis and to prevent organ transplant rejection. They work by stopping cancer cell growth and preventing the spread of the cells. Votrient is only available as a brand name drug. Compare kinase inhibitors.
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Votrient Side Effects

Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal or stomach pain or tenderness

black, tarry stools

bleeding gums

blood in the urine or stools

blurred vision

chest pain

chills

clay colored stools

cloudy urine

constipation

cough

coughing up blood

dark urine

decreased appetite

depressed mood

difficulty with breathing or swallowing

dizziness

dry skin and hair

feeling cold

fever

hair loss

headache

hoarseness or husky voice

increased menstrual flow or vaginal bleeding

itching or skin rash

loss of appetite

lower back or side pain

muscle cramps and stiffness

nausea and vomiting

nervousness

nosebleeds

painful or difficult urination

pale skin

paralysis

pinpoint red spots on the skin

pounding in the ears

prolonged bleeding from cuts

red or black, tarry stools

red or dark brown urine

redness, swelling, or pain of the skin

scaling of the skin on the hands and feet

slow or fast heartbeat

sore throat

sores, ulcers, or white spots on the lips or in the mouth

swelling of the feet or lower legs

swollen glands

tingling of the hands and feet

ulceration of the skin

unusual bleeding or bruising

unusual tiredness or weakness

weight gain

yellow eyes or skin

Less common

Bleeding from rectum or bloody stools

bloody nose

chest discomfort

confusion

fainting

irregular or slow heart rate

numbness or tingling in the face, arms, or legs

pain or discomfort in the shoulders, arms, jaw, back, or neck

sweating

swelling or puffiness of the face

trouble speaking, thinking, or walking

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Change in hair color

change in taste

decreased weight

diarrhea

hair loss

lack or loss of strength

loss of taste

thinning of the hair

weight loss

Less common

Acid or sour stomach

belching

heartburn

indigestion

stomach discomfort, upset, or pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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