The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Nerve pain
- Numbness or tingling in the fingers or toes (peripheral neuropathy)
- Feeling very weak
- Constipation
- Nausea
- Vomiting
- Diarrhea
- Stomach pain or cramps
- Hair loss
- Trouble walking or moving
- Problems with urination
Less Common Side Effects
- Pain or redness at the infusion site
- Feeling dizzy
- Lower appetite
- Mouth sores
- Jaw or throat pain
- Bone or muscle pain
- Headache
- Trouble balancing
- Rash
- Changes in blood pressure
- Low red blood cell counts (anemia)
- Low white blood cell counts
- Low platelets
Vincristine serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Problems with the digestive system: severe constipation, stomach pain, can’t pass gas, bloating, fever, chills
- Problems with the nervous system: numbness, tingling, or pain in the fingers or toes; vision, movement, balance, or hearing problems; confusion
- Lung problems: sudden or worsening cough, having trouble catching your breath, fast breathing
- Liver problems: pain in the upper right side of your stomach, yellow skin or eyes
Source: DailyMed
The following Vincristine side effects have also been reported
Along with their needed effects, medicines like vincristine can sometimes cause unwanted effects such as blood problems, nervous system problems, loss of hair, and other side effects. These and others are described below. Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. Discuss these possible effects with your doctor.
Check with your doctor immediately if any of the following side effects occur:
Less common
Pain or redness at place of injection
Check with your doctor as soon as possible if any of the following side effects occur:
More common
Blurred or double vision
difficulty in walking
drooping eyelids
headache
jaw pain
joint pain
lower back or side pain
numbness or tingling in fingers and toes
pain in fingers and toes
pain in testicles
stomach cramps
swelling of feet or lower legs
weakness
Less common
Agitation
bed-wetting
confusion
convulsions (seizures)
decrease or increase in urination
dizziness or lightheadedness when getting up from a lying or sitting position
hallucinations (seeing, hearing, or feeling things that are not there)
lack of sweating
loss of appetite
mental depression
painful or difficult urination
trouble in sleeping
unconsciousness
Rare
Sores in mouth and on lips
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects may occur that usually do not need medical attention. This medicine often causes a temporary loss of hair. After treatment with vincristine has ended, or sometimes even during treatment, normal hair growth should return.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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