The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Low white blood cells (92%)
- Low red blood cells (83%)
- Higher liver enzymes (up to 67%)
- Nausea (up to 44%)
- Weakness (36%)
- Constipation (35%)
- Redness, pain, and warmth around injection site (28%)
- Numbness and tingling in fingers and/or toes (25%)
- Vomiting (20%)
Less Common Side Effects
- Diarrhea
- Hair loss
- Pain in blood vein
- Trouble breathing
Vinorelbine serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious infections (from low WBCs): temperature of 100.4F (with or without other symptoms, such as chills), cough, muscle aches, very fast heartbeat, confusion
- Other serious blood problems: severe tiredness, nosebleeds, unexplained bruising
- Serious lung problems: trouble breathing, fever, chest tightness, cough, rattling or clicking sound when breathing, fast breathing
- Serious gut problems: sudden stomach pain, bloating, nausea and vomiting, passing gas often
Source: DailyMed
The following Vinorelbine side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
Black, tarry stools
bleeding gums
bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
blood in the urine or stools
bluish color of the skin
burning, numbness, tingling, or painful sensations
changes in skin color
chills
clay-colored stools
dark urine
decreased appetite
dizziness
feeling of fullness in the ears
headache
hoarseness
itching, skin rash
loss of appetite
loss of balance
loss of hearing
lower back or side pain
muscle pains, cramps, or stiffness
painful or difficult urination
pale skin
pinpoint red spots on the skin
ringing or buzzing in the ears
sores, ulcers, or white spots on the lips or in the mouth
stomach pain or tenderness
swelling of the feet or lower legs
swollen glands
tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
trouble in hearing
troubled breathing with exertion
unsteadiness or awkwardness
unusual bleeding or bruising
unusual tiredness or weakness
yellow eyes or skin
Less common
Chest tightness
increased sensitivity to pain or touch
overactive reflexes, followed by underactive reflexes
trouble breathing
Rare
Agitation
chest discomfort
confusion
decreased awareness or responsiveness
decreased urine output
hostility
irritability
loss of consciousness
lower abdominal cramping
muscle twitching
pain or discomfort in the arms, jaw, back, or neck
rapid weight gain
seizures
severe sleepiness
swelling of the face, ankles, or hands
unusual drowsiness, dullness, or feeling of sluggishness
vomiting
Incidence not known
blistering or sloughing of the skin
blurred vision
change in walking and balance
clumsiness or unsteadiness
coughing that sometimes produces a pink frothy sputum
difficult, fast, noisy breathing
difficulty in swallowing
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
fainting
fast, pounding, or irregular heartbeat or pulse
hives or welts
increased sweating
increased thirst
indigestion
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
lightheadedness
nervousness
pain or burning in the throat
pain, redness, or swelling in the arm or leg
pains in the stomach, side, or abdomen, possibly radiating to the back
pale skin
pounding in the ears
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
redness, swelling, or pain of the skin
scaling of the skin on the hands and feet
slow heartbeat
ulceration of the skin
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
chills
confusion
fainting
fast heartbeat
lightheadedness
lower back or side pain
painful or difficult urination
partial or slight paralysis
rapid, shallow breathing
severe constipation
severe stomach pain
severe vomiting
sores, ulcers, or white spots on the lips or in the mouth
swollen glands
unusual bleeding or bruising
unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Change in taste
difficulty in moving
impaired hearing
joint pain or swelling
lack or loss of strength
thinning or loss of hair
Incidence not known
Back pain
cracked, dry, scaly skin
feeling of warmth or heat
flushing or redness of the skin, especially on the face and neck
jaw pain
pain and redness of the skin at the place of earlier radiation treatment
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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