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Venclexta

Venclexta Side Effects

Sonja Jacobsen, PharmD, BCPS, BCOPConnie Zheng, PharmD
Reviewed by Sonja Jacobsen, PharmD, BCPS, BCOP, Connie Zheng, PharmD
Last reviewed on November 16, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Low white blood cell count (50%)
  • Diarrhea (43%)
  • Nausea (42%)
  • Upper respiratory tract infection (36%)
  • Low red blood cell count (33%)
  • Tiredness (32%)
  • Low platelet count (29%)
  • Muscle and joint pain (29%)
  • Swelling in arms, legs, hands, or feet (22%)
  • Stomach pain (18%)
  • Headache (18%)
  • Rash (18%)
  • Vomiting (16%)
  • Constipation (16%)

Please note: These side effects were reported by people who took only Venclexta (venetoclax). The side effects you experience might differ if you're taking Venclexta (venetoclax) with other anticancer medications.

Less Common Side Effects

  • Fever
  • Infection in the blood
  • Trouble breathing
  • Infection in the lungs
  • Cough
  • Sore throat
  • Dizziness
  • Low blood pressure
  • Painful mouth sores

Venclexta serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Tumor lysis syndrome: fever, chills, nausea or vomiting, confusion, shortness of breath, seizures, irregular heartbeat, dark or cloudy urine, muscle or joint pain, unusual tiredness
  • Serious infections: body aches, chills, fever, headache, new cough, sore throat, feeling tired

Source: DailyMed

The following Venclexta side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
  • Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
  • Tumor lysis syndrome (TLS)—nausea, vomiting, diarrhea, decrease in the amount of urine, dark urine, unusual weakness or fatigue, confusion, muscle pain or cramps, fast or irregular heartbeat, joint pain
  • Unusual bruising or bleeding

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

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