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Specialty Drug
EPOPROSTENOL is used to treat primary pulmonary hypertension. Compare prostacyclines.
Prescription Settings
90 vials
90 vials

Veletri Side Effects

What should I watch for?

Visit your doctor or health care professional for regular checks on your progress. Report any unusual or severe side effects promptly.

While you are receiving this medicine, you may be more susceptible to infection because of your intravenous catheter. Unfortunately, symptoms of infection can be similar to some of the side effects of this medicine, such as fever, chills or other 'flu-like' symptoms. Contact your doctor or health care professional if you experience any unusual symptoms. Inspect the area around your catheter frequently. Alert your doctor or health care professional if there is any unusual redness or pain.

Despite receiving this medicine, your condition may worsen and you may need your dose adjusted. Call your doctor or health care professional if your condition gets worse.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal or stomach pain

arm, back, or jaw pain

bladder pain

bleeding gums

bloating or swelling of the face, arms, hands, lower legs, or feet

bloody or cloudy urine

blurred vision

changes in skin color

chest congestion

chest pain or discomfort

chest tightness or heaviness


cold hands and feet




cough or hoarseness

coughing up blood

decreased urine



difficult, burning, or painful urination

difficulty with breathing or swallowing

dilated neck veins

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

dry mouth

extreme fatigue

fast, pounding, or irregular heartbeat or pulse

feeling of warmth



incoherent speech

increased menstrual flow or vaginal bleeding

increased thirst

increased urination

local infection at the catheter site

loss of appetite

metallic taste

muscle pain or cramps

muscle weakness

nausea or vomiting


numbness or tingling in the hands, feet, or lips

pain at the injection site

pain, redness, or swelling in the arm or leg

paleness of the skin

prolonged bleeding from cuts

rapid weight gain

red or black, tarry stools

redness of the face, neck, arms, and occasionally, upper chest


swelling of the face, fingers, feet, or lower legs

tightness in the chest

tingling of the hands or feet

unusual tiredness or weakness

weight gain or loss

Less common

Altered or abnormal touch sensation or sensitivity

blue lips and fingernails

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

coughing that sometimes produces a pink frothy sputum

difficult, fast, or noisy breathing

inability to speak

increased sweating

numbness or tingling in the hands, feet, or lips

pain or discomfort in the arms, jaw, back, or neck


severe or sudden headache

severe pain in the chest

slurred speech

sudden onset of severe breathing

temporary blindness

weakness in the arm or leg on one side of the body, sudden and severe

weakness or heaviness of the legs

Incidence not known

Feeling of fullness

high fever

pinpoint red spots on the skin

sensitivity to heat

sores, ulcers, or white spots on the lips or in the mouth

swollen glands

trouble sleeping

troubled breathing with exertion

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Change in vision

difficulty having a bowel movement (stool)

difficulty with moving


hives or welts

impaired vision


joint pain

lack of appetite

lack or loss of strength

loss of interest or pleasure

muscle pains or stiffness

redness of the skin

shakiness in the legs, arms, hands, or feet

skin rash, encrusted, scaly and oozing

sores on the skin

swollen joints


trembling or shaking of the hands or feet

trouble concentrating

Less common

Acid or sour stomach


blurred vision or other changes in vision

excess air or gas in the stomach or intestines


leg cramps

passing gas

sleepiness or unusual drowsiness

stomach discomfort or upset

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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