Velcade Side Effects
What should I watch for?
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
In some cases, you may be given additional medicines to help with side effects. Follow all directions for their use.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
You may need blood work done while you are taking this medicine.
In some patients, this medicine may cause a serious brain infection that may cause death. If you have any problems seeing, thinking, speaking, walking, or standing, tell your doctor right away. If you cannot reach your doctor, urgently seek other source of medical care.
Check with your doctor or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.
Do not become pregnant while taking this medicine or for at least 2 to 7 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for at least 2 to 4 months after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 2 months after stopping it.
This medicine may interfere with the ability to have a child. You should talk with your doctor or health care professional if you are concerned about your fertility.
Common and Rare Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Black, tarry stools
blood in the urine or stools
body aches or pain
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
cough producing mucus
difficult or labored breathing
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
increase in heart rate
loss of voice
lower back or side pain
painful blisters on the trunk of the body
painful or difficult urination
pinpoint red spots on the skin
tightness in the chest
troubled breathing with exertion
ulcers, sores, or white spots in the mouth
unsteadiness or awkwardness
unusual bleeding or bruising
unusual tiredness or weakness
weakness in the arms, hands, legs, or feet
Dilated neck veins
general feeling of discomfort or illness
increased sensitivity to pain
increased sensitivity to touch
swelling of the face, fingers, feet, or lower legs
thickening of bronchial secretions
tingling in the hands and feet
Incidence not known
blistering, peeling, loosening of the skin
change in consciousness
coughing or vomiting blood
deep or fast breathing with dizziness, numbness to feet, hands, and around the mouth
general tiredness and weakness
loss of consciousness
pain in the stomach, side, or abdomen, possibly radiating to the back
persistent bleeding or oozing from puncture sites, mouth, or nose
pounding, slow heartbeat
red skin lesions, often with a purple center
red, irritated eyes
seeing, hearing, or feeling things that are not there
stomach pain and tenderness
upper right stomach pain
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
difficulty having a bowel movement
difficulty with moving
feeling unusually cold or shivering
loss of appetite
loss of taste
muscle pain or stiffness
pain in the joints
pain in the limb
stomach discomfort, upset, or pain
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.