Calcitriol ointment (Vectical) is used to treat an autoimmune skin condition called plaque psoriasis in adults and children 2 years and older. It's a form of vitamin D, or a vitamin D analogue, that's thought to help regulate the immune system to treat psoriasis. The ointment is applied onto affected areas of the body twice a day. Side effects might include skin discomfort. This prescription medication is available under the brand name Vectical and as a lower-cost generic.
Mild-to-moderate plaque psoriasis
Calcitriol ointment (Vectical) is a vitamin D analog, a form of vitamin D. It's not known how it exactly works to treat psoriasis, which is an autoimmune skin condition. But some studies suggest that vitamin D can help calm down your immune system. This might lessen skin inflammation and slow down how fast skin cells are made, which are both involved in psoriasis.
Source: DailyMed
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
Generally well tolerated with very few side effects
Safe to use on children age 2 or older
Available as a lower-cost generic
Not for severe plaque psoriasis
Can't apply onto the face
Might not be the best option for people who are taking calcium supplements or high doses of vitamin D
Apply just enough calcitriol ointment (Vectical) to cover the area(s) of skin that has psoriasis only. Gently rub the ointment into the skin until you don't see the medication anymore. Apply in the morning and at night.
Only apply calcitriol ointment (Vectical) on top of the skin. Avoid applying the ointment onto the face or lips. Don't put the medication into your mouth, eyes, or vagina because it can be harmful.
Wash your hands after you apply calcitriol ointment (Vectical) onto the skin, unless you're treating psoriasis on your hands. Washing your hands helps prevent leftover medication from getting onto other things, including your mouth or eyes.
Don't place a waterproof bandage over the area(s) where you applied calcitriol ointment (Vectical). This lowers your chances of getting more medication absorbed into the skin and having side effects.
Be sure to let your care team know about any medications or supplements you're taking or planning to take. Calcium supplements, medications that can raise your calcium levels, and high doses of vitamin D can put you at risk of having high calcium levels while you're using calcitriol ointment (Vectical).
Keep calcitriol ointment (Vectical) somewhere safe at room temperature. Don't refrigerate or freeze the medication.
Calcitriol ointment (Vectical) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk factors: Covering the treated area with a bandage | Taking medications that raise calcium levels, including calcium supplements | Taking a high dose of vitamin D
Some people who used calcitriol ointment (Vectical) had high calcium levels. This might happen because the medication is a form of vitamin D and vitamin D affects the levels of calcium in the body.
Covering the treated area with a bandage while using calcitriol ointment (Vectical) raises the risk of high calcium levels, as it allows more medication to be absorbed through the skin. You might also be at risk if you take calcium supplements, other medications that can raise your calcium levels, and high doses of vitamin D. Let your prescriber know if you have signs or symptoms of high calcium levels, such as weakness, tiredness, low appetite, constipation, and mood changes like depression.
Dosage | Quantity | Price as low as | Price per unit |
---|---|---|---|
100g of 3mcg/g | 1 tube | $685.39 | $685.39 |
Apply calcitriol ointment (Vectical) to the affected areas of your body twice a day (morning and evening).
The maximum amount of medication that you can apply onto the skin each week depends on your age.
Age 7 years or older: Maximum 200 grams per week.
Age 2 to 6 years: Maximum 100 grams per week.
Mild-to-moderate plaque psoriasis
Plaque psoriasis - cream, ointment, foam
Scalp psoriasis - foam, solution
Acne - 0.1% strength only
Plaque psoriasis - 0.05% and 1% strengths
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Gil, A., et al. (2018). Vitamin D: Classic and novel actions. Annals of Nutrition and Metabolism.
Kim, G. K. (2010). The rationale behind topical vitamin d analogs in the treatment of psoriasis: Where does topical calcitriol fit in? The Journal of Clinical and Aesthetic Dermatology.
Padagis Israel Pharmaceuticals Ltd. (2023). Calcitriol ointment [package insert]. DailyMed.
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