Skip to main content
Trelegy Ellipta

Trelegy Ellipta Side Effects

Robert Chad Hakim, PharmD, BCCCPKristianne Hannemann, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Kristianne Hannemann, PharmD
Last reviewed on July 3, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

COPD:

  • Headache (4%)
  • Back pain (4%)
  • Changes in taste (2%)
  • Diarrhea (2%)

Asthma:

  • Common cold symptoms (up to 17%)
  • Headache (up to 9%)
  • Upper respiratory tract infection (up to 7%)
  • Bronchitis (up to 5%)
  • Sinus infection (up to 3%)
  • Back pain (up to 3%)

Less Common Side Effects

COPD:

  • Cough
  • Mouth and throat pain
  • Oral thrush
  • Upper respiratory tract infection
  • Stomach flu
  • Bronchitis
  • Flu
  • Urinary tract infections (UTI)
  • Constipation
  • Joint pain
  • Hoarseness

Asthma:

  • Urinary tract infection (UTI)
  • Voice changes
  • Mouth and throat pain
  • Cough
  • Runny nose
  • Hoarseness

Trelegy Ellipta serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Pneumonia: more mucus, mucus changing color, fever, chills, coughing more than usual, more trouble breathing
  • Serious allergic reaction: rash, hives, swelling of your face or tongue, difficulty breathing
  • Sudden narrowing of the airways: worsening trouble breathing, coughing, wheezing
  • Heart problems: a fast or irregular heartbeat, feeling your heartbeat, chest pain
  • Eye problems: eye pain, nausea or vomiting, blurred vision, seeing halos or bright colored lights, red eyes
When do Trelegy Ellipta possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Cough
Sore throat
Risk of respiratory tract infection
Risk of oral thrush
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following Trelegy Ellipta side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
  • Increase in blood pressure
  • Low adrenal gland function—nausea, vomiting, loss of appetite, unusual weakness or fatigue, dizziness
  • Muscle pain or cramps
  • Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
  • Thrush—white patches in the mouth
  • Trouble passing urine
  • Wheezing or trouble breathing that is worse after use

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

GoodRx icon

Other Beta Agonist / Anticholinergics / Corticosteroid Combinations side effects articles

Was this page helpful?