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Tradjenta

Tradjenta Side Effects

Robert Chad Hakim, PharmD, BCCCPCydnee Ng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Cydnee Ng, PharmD
Last reviewed on July 28, 2026

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Note: Side effects were from people who took Tradjenta (linagliptin) by itself or with other diabetes medications.

Tradjenta serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Inflammation of the pancreas (pancreatitis): severe stomach pain that spreads to your back, nausea, vomiting
  • Severe allergic reaction: rash; hives; peeling skin; swelling of face, tongue, or throat; trouble breathing
  • Severe skin reaction: itchy skin, rash with blisters, sores

Source: DailyMed

The following Tradjenta side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Anxiety

blurred vision

chills

cold sweats

confusion

cool, pale skin

depression

dizziness

fast heartbeat

headache

increased hunger

loss of consciousness

nausea

nightmares

seizures

shakiness

slurred speech

unusual tiredness or weakness

Incidence not known

Bloating

constipation

cough

fever

hives, welts, itching, or skin rash

large, hard skin blisters

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

loss of appetite

pains in the stomach, side, or abdomen, possibly radiating to the back

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

redness of the skin

severe joint pain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Muscle aches

sore throat

stuffy or runny nose

Less common

Diarrhea

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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