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How Much Is Topiramate Without Insurance?

Brookie MadisonAmy B. Gragnolati, PharmD, BCPS
Published on November 1, 2024

Key takeaways:

  • Topiramate (Topamax) is a prescription-only medication used to treat epilepsy (seizure disorder) and prevent migraines. 

  • What you’ll pay for topiramate will depend on the formulation and daily dose you take, along with the pharmacy you use, and where it’s located. Without insurance, the average cost for a 30-day supply of 200 mg topiramate (60 tablets) is around $156.07

  • There are coupons and savings programs that may be able to help you pay for topiramate. 

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Topiramate (Topamax) is a prescription-only medication used to treat certain types of seizures in people with epilepsy (seizure disorder). The types of seizures topiramate can treat are: primary generalized tonic-clonic, partial onset, and Lennox-Gastaut syndrome seizures. The medication is also FDA approved to help prevent migraines

Epileptic seizures occur when nerve cells in the brain send the wrong signals to the body at too fast a pace, potentially causing involuntary movement. To prevent seizures, topiramate stops the brain from sending these disorganized signals to the body.

Topiramate basics

The chart below provides a snapshot of information about topiramate.

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Topiramate Basics

Generic names

Topiramate, Topiramate extended-release (ER)

Brand names

Immediate-release (IR) tablets: Topamax
ER capsules: Qudexy XR
IR oral liquid: Eprontia

FDA-approved uses

• Monotherapy, or add-on therapy, for certain types of epilepsy in adults and children age 2 and older
• Migraine headache prevention in adults and children who are at least 12 years old

Dosage forms and doses

IR tablets and ER capsules: 25 mg, 50 mg, 100 mg, and 200 mg 
IR capsules: 15 mg and 25 mg
Oral liquid: 25 mg/mL

Qudexy XR also comes as a 150 mg tablet.

The immediate-release tablets, capsules, and liquid are typically taken twice a day. The ER capsules are typically taken once a day. All topiramate products can be taken with or without food.

Off-label uses

Alcohol use disorder
Binge eating disorder
Bulimia nervosa
Weight loss

How it works

Prevents the brain from sending disorganized signals to the body

Benefits

Available in liquid form if you have trouble swallowing pills 
IR and ER options
Suitable for children and adults 

Possible side effects

Drowsiness
Weight loss
Nervousness
Nausea
Pins and needles sensation
Dizziness

Is topiramate covered by insurance?

Health insurance plans typically cover epilepsy and migraine treatments, including many medications. For example, all Medicare Part D plans cover generic topiramate. But they may not cover brand-name forms like Topamax.

If you have insurance, check your plan’s summary of benefits and coverage and formulary to determine whether generic topiramate or the brand-name options are covered.

How insurance covers topiramate

Most health insurance plans that cover generic topiramate don’t require a prior authorization or step therapy. However, a prior authorization is required for about 1 in 14 people with Medicare.

The following chart shows the likelihood of having coverage for topiramate, as well as needing a prior authorization or to do step therapy, with commercial insurance, Affordable Care Act (ACA), Medicare, and Medicaid plans.

Insurance Coverage for Generic Topiramate

Insurance type

Enrollees covered for this medication

Enrollees required to get a prior authorization

Enrollees required to do step therapy

Commercial (not including plans purchased via an ACA marketplace)

99.3%

.1%

.06%

ACA plans

99.7%

0%

.31%

Medicare, including original Medicare and Medicare Advantage plans

100%

7%

0%

Medicaid, including state-run and managed care plans

99.9%

2.9%

0%

Source: Managed Markets Insight & Technology, LLC™, as of September 26, 2024. (See methodology below.)

Tips if your medication isn’t covered by insurance

Here are a few options if your insurance does not cover generic topiramate or brand-name forms such as Topamax:

GoodRx icon
  • How it works: Topiramate (Topamax) works by blocking your brain from sending certain electrical or chemical signals that could trigger a seizure.

  • Side effects: The most common side effects for topiramate include dizziness, pins and needles sensation, nervousness, and nausea. 

  • Topiramate interactions: Topiramate interacts with other medications in a variety of ways. For instance, it can make oral birth control less effective.

How much does topiramate cost without insurance?

If you don’t have health insurance, the price of generic topiramate or brand-name Topamax may depend on the following factors: 

  • Your prescribed dosage

  • Your dosage form (tablet, capsule, or solution)

  • Whether you’re getting a brand-name or generic version

  • The fill amount (90-day supply versus 30-day supply)

  • Your geographic location

  • The specific pharmacy you use

The charts below contain recent average retail prices for 30-day supplies of generic topiramate.

Generic topiramate IR 

Average retail price

25 mg (60 tablets)

$66.36

50 mg (60 tablets)

$112.35

100 mg (60 tablets)

$145.52

200 mg (60 tablets)

$156.07

15 mg (60 capsules)

$127.91

25 mg (60 capsules)

$161.38

Generic topiramate ER  

Average retail price

25 mg (60 capsules)

$637.54

50 mg (30 capsules)

$393.54

100 mg (30 capsules)

$817.32

200 mg (30 capsules)

$1018.84

200 mg (60 capsules)

$2098.99

Brand-name topiramate

As mentioned, topiramate is available in several brand-name versions. Generic medications typically cost less than their brand-name counterparts. However, topiramate oral liquid is only available as brand-name Eprontia.

The charts below contain recent average retail prices for 30-day supplies of the brand-name versions of topiramate: Topamax, Qudexy XR, and Eprontia.

Topamax IR 

Average retail price

25 mg (60 tablets)

$482.67

50 mg (60 tablets)

$943.83

100 mg (60 tablets)

$1345.14

200 mg (60 tablets)

$1535.51

15 mg (60 capsules)

$655.89

25 mg (60 capsules)

$599.25

Qudexy XR 

Average retail price

25 mg (30 capsules)

$354.70

50 mg (30 capsules)

$459.20

100 mg (30 capsules)

$897.94

150 mg (30 capsules)

$1133.24

200 mg (30 capsules)

$1237.75

200 mg (60 capsules)

$2463.87

Eprontia oral solution

Average retail price

120 mL of 25 mg/mL (1 bottle)

$403.91

240 mL of 25 mg/mL (1 bottle)

$719.85

473 mL of 25 mg/mL (1 bottle)

$893.27

Ways to save on brand-name topiramate

You may be able to save money on brand-name topiramate if you qualify for patient assistance programs. Here’s a summary of the programs and savings options available for each version:

  • Topamax: If you have private or commercial insurance, you may qualify for a coupon for Topamax through the Topamax Savings Program. With this program, you could pay $4 per prescription fill, if you use a pharmacy that participates and accepts the coupon. The coupon could save you up to $1,800 on 12 prescription fills per calendar year. The program is not available to people with Medicare, Medicaid, or other government-funded health insurance plans.

  • Qudexy XR: The manufacturer of Qudexy XR makes an authorized generic, which costs less than the brand-name version.

  • Eprontia: You may be able to get Eprontia for $0 if you have commercial or private insurance. If you have government-sponsored insurance — such as Medicare, Medicaid, or Tricare — the maker of Eprontia offers a bridge program that covers the cost of the medication if insurance approval takes more than 48 hours. You may still qualify for assistance if you don’t have insurance. You can find more information on copay assistance and other types of financial aid on the Azurity Solutions page for Eprontia.

How to afford topiramate without insurance

Here are five ways to save on generic topiramate without insurance.

1. Use a GoodRx coupon

With a GoodRx coupon, you may be able to pay a lower price for your prescription.

Here’s how to get a coupon:

  • Visit www.goodrx.com or install the GoodRx app on your mobile device.

  • Type “Topiramate” in the search field. Be sure to select “Topiramate (generic Qudexy XR)” or “Topiramate (generic Topamax)” in the drop-down menu.

  • Select the correct dose and quantity, and set your location.

  • Choose whether you want to receive your coupon via text or email, print it out, or save it on the GoodRx app. 

  • Show the coupon at the pharmacy when you pick up your medication. Or present the coupon to your pharmacy’s staff early in the filling process, such as when you first receive your prescription, to help prevent delays at the pick-up counter.

2. Request a 90-day supply

Ask your healthcare professional to write you a prescription for a 90-day supply of topiramate instead of a 30-day supply to compare costs. A 3-month supply may be a better value and reduce your trips to the pharmacy. If you have insurance that covers topiramate, ask about discounts for using your plan’s mail-order pharmacy.

3. Compare prices at various pharmacies

GoodRx can easily compare costs at different pharmacies to help you find the best topiramate price in your area.

4. Talk to your prescriber about alternatives

If you are concerned about the cost of your medication, tell your prescriber. There may be another medication or another version of your medication that better fits your budget, while still adequately treating your condition.

5. Use your tax-advantaged healthcare expense funds

If you have a health savings account (HSA), flexible spending account (FSA), or health reimbursement arrangement (HRA), using those funds to purchase your medication can reduce your out-of-pocket costs through tax savings.

The bottom line

How much you’ll pay for topiramate (Topamax) will depend on what form of the medication you’re prescribed and your daily dose. It will also depend on what pharmacy you choose and where it’s located.

Some health insurance plans may cover the cost of generic topiramate. Brand-name versions of topiramate, such as Topamax, are less likely to be covered by insurance. But you may be able to use coupons from GoodRx or patient assistance programs to help you afford generic or brand-name topiramate.

If you don’t have insurance, you may be able to save on your topiramate prescription by comparing prices at different pharmacies or requesting a larger supply. 

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Why trust our experts?

Brookie Madison
Written by:
Brookie Madison
Brookie Madison is a freelance writer, communications professional, and content creator. She has more than eight years of experience covering topics including consumer health, personal finance, mental health, community outreach, education, and more.
Cindy George, MPH
Cindy George is the senior personal finance editor at GoodRx. She is an endlessly curious health journalist and digital storyteller.
Amy B. Gragnolati, PharmD, BCPS
Amy Gragnolati, PharmD, BCPS, is a pharmacy editor for GoodRx. Amy currently holds her pharmacist license in Georgia and California.

Methodology

National prescription coverage data for each medication was obtained from Managed Markets Insight & Technology (MMIT), reflecting health insurance coverage as of September 2024. The percentage of enrollees in plans that cover each medication was calculated by dividing the number of enrollees covered for the medication within a specific insurance channel (e.g., ACA, Medicare, Medicaid) by the total number of enrollees in all plans within that channel. Similarly, the percentage of enrollees in plans with prior authorization was determined by calculating the proportion of enrollees in plans that require prior authorization for the medication within each channel. The percentage of enrollees in plans with step therapy was calculated as the proportion of enrollees in plans that impose step therapy requirements for the medication in each channel. These estimates, derived from national MMIT coverage data, provide insight into the health insurance coverage landscape for each medication, taking into account restrictions such as prior authorization, step therapy, and quantity limits. The percentages are expressed relative to the total population of enrollees covered by insurance across various channels, including ACA, commercial (excluding ACA) plans, Medicare, and Medicaid (both state and managed Medicaid).

References

HealthCare.gov. (n.d.). Appealing a health plan decision.

Medicaid.gov. (n.d.). Managed care.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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