Key takeaways:
Topiramate (Topamax) is a prescription-only medication used to treat epilepsy (seizure disorder) and prevent migraines.
What you’ll pay for topiramate will depend on the formulation and daily dose you take, along with the pharmacy you use, and where it’s located. Without insurance, the average cost for a 30-day supply of 200 mg topiramate (60 tablets) is around $156.07.
There are coupons and savings programs that may be able to help you pay for topiramate.
Topiramate (Topamax) is a prescription-only medication used to treat certain types of seizures in people with epilepsy (seizure disorder). The types of seizures topiramate can treat are: primary generalized tonic-clonic, partial onset, and Lennox-Gastaut syndrome seizures. The medication is also FDA approved to help prevent migraines.
Epileptic seizures occur when nerve cells in the brain send the wrong signals to the body at too fast a pace, potentially causing involuntary movement. To prevent seizures, topiramate stops the brain from sending these disorganized signals to the body.
The chart below provides a snapshot of information about topiramate.
Generic names | Topiramate, Topiramate extended-release (ER) |
Brand names | • Immediate-release (IR) tablets: Topamax |
FDA-approved uses | • Monotherapy, or add-on therapy, for certain types of epilepsy in adults and children age 2 and older |
Dosage forms and doses | • IR tablets and ER capsules: 25 mg, 50 mg, 100 mg, and 200 mg Qudexy XR also comes as a 150 mg tablet. The immediate-release tablets, capsules, and liquid are typically taken twice a day. The ER capsules are typically taken once a day. All topiramate products can be taken with or without food. |
Off-label uses | • Alcohol use disorder |
How it works | Prevents the brain from sending disorganized signals to the body |
Benefits | • Available in liquid form if you have trouble swallowing pills |
Possible side effects | • Drowsiness |
Health insurance plans typically cover epilepsy and migraine treatments, including many medications. For example, all Medicare Part D plans cover generic topiramate. But they may not cover brand-name forms like Topamax.
If you have insurance, check your plan’s summary of benefits and coverage and formulary to determine whether generic topiramate or the brand-name options are covered.
Most health insurance plans that cover generic topiramate don’t require a prior authorization or step therapy. However, a prior authorization is required for about 1 in 14 people with Medicare.
The following chart shows the likelihood of having coverage for topiramate, as well as needing a prior authorization or to do step therapy, with commercial insurance, Affordable Care Act (ACA), Medicare, and Medicaid plans.
Insurance type | Enrollees covered for this medication | Enrollees required to get a prior authorization | Enrollees required to do step therapy |
---|---|---|---|
Commercial (not including plans purchased via an ACA marketplace) | 99.3% | .1% | .06% |
99.7% | 0% | .31% | |
Medicare, including original Medicare and Medicare Advantage plans | 100% | 7% | 0% |
Medicaid, including state-run and managed care plans | 99.9% | 2.9% | 0% |
Source: Managed Markets Insight & Technology, LLC™, as of September 26, 2024. (See methodology below.)
Here are a few options if your insurance does not cover generic topiramate or brand-name forms such as Topamax:
Talk to your prescriber about alternative medications.
Request a formulary exception from your insurer. If the request is denied, consider filing an appeal for coverage.
Try enrolling in a patient assistance program.
Use a GoodRx coupon for potential savings.
Consider changing your prescription medication coverage during your next open enrollment period.
How it works: Topiramate (Topamax) works by blocking your brain from sending certain electrical or chemical signals that could trigger a seizure.
Side effects: The most common side effects for topiramate include dizziness, pins and needles sensation, nervousness, and nausea.
Topiramate interactions: Topiramate interacts with other medications in a variety of ways. For instance, it can make oral birth control less effective.
If you don’t have health insurance, the price of generic topiramate or brand-name Topamax may depend on the following factors:
Your prescribed dosage
Your dosage form (tablet, capsule, or solution)
Whether you’re getting a brand-name or generic version
The fill amount (90-day supply versus 30-day supply)
Your geographic location
The specific pharmacy you use
The charts below contain recent average retail prices for 30-day supplies of generic topiramate.
Generic topiramate IR | Average retail price |
---|---|
25 mg (60 tablets) | |
50 mg (60 tablets) | |
100 mg (60 tablets) | |
200 mg (60 tablets) | |
15 mg (60 capsules) | |
25 mg (60 capsules) |
Generic topiramate ER | Average retail price |
---|---|
25 mg (60 capsules) | |
50 mg (30 capsules) | |
100 mg (30 capsules) | |
200 mg (30 capsules) | |
200 mg (60 capsules) |
As mentioned, topiramate is available in several brand-name versions. Generic medications typically cost less than their brand-name counterparts. However, topiramate oral liquid is only available as brand-name Eprontia.
The charts below contain recent average retail prices for 30-day supplies of the brand-name versions of topiramate: Topamax, Qudexy XR, and Eprontia.
Topamax IR | Average retail price |
---|---|
25 mg (60 tablets) | |
50 mg (60 tablets) | |
100 mg (60 tablets) | |
200 mg (60 tablets) | |
15 mg (60 capsules) | |
25 mg (60 capsules) |
Qudexy XR | Average retail price |
---|---|
25 mg (30 capsules) | |
50 mg (30 capsules) | |
100 mg (30 capsules) | |
150 mg (30 capsules) | |
200 mg (30 capsules) | |
200 mg (60 capsules) |
Eprontia oral solution | Average retail price |
---|---|
120 mL of 25 mg/mL (1 bottle) | |
240 mL of 25 mg/mL (1 bottle) | |
473 mL of 25 mg/mL (1 bottle) |
You may be able to save money on brand-name topiramate if you qualify for patient assistance programs. Here’s a summary of the programs and savings options available for each version:
Topamax: If you have private or commercial insurance, you may qualify for a coupon for Topamax through the Topamax Savings Program. With this program, you could pay $4 per prescription fill, if you use a pharmacy that participates and accepts the coupon. The coupon could save you up to $1,800 on 12 prescription fills per calendar year. The program is not available to people with Medicare, Medicaid, or other government-funded health insurance plans.
Qudexy XR: The manufacturer of Qudexy XR makes an authorized generic, which costs less than the brand-name version.
Eprontia: You may be able to get Eprontia for $0 if you have commercial or private insurance. If you have government-sponsored insurance — such as Medicare, Medicaid, or Tricare — the maker of Eprontia offers a bridge program that covers the cost of the medication if insurance approval takes more than 48 hours. You may still qualify for assistance if you don’t have insurance. You can find more information on copay assistance and other types of financial aid on the Azurity Solutions page for Eprontia.
Here are five ways to save on generic topiramate without insurance.
With a GoodRx coupon, you may be able to pay a lower price for your prescription.
Here’s how to get a coupon:
Visit www.goodrx.com or install the GoodRx app on your mobile device.
Type “Topiramate” in the search field. Be sure to select “Topiramate (generic Qudexy XR)” or “Topiramate (generic Topamax)” in the drop-down menu.
Select the correct dose and quantity, and set your location.
Choose whether you want to receive your coupon via text or email, print it out, or save it on the GoodRx app.
Show the coupon at the pharmacy when you pick up your medication. Or present the coupon to your pharmacy’s staff early in the filling process, such as when you first receive your prescription, to help prevent delays at the pick-up counter.
Ask your healthcare professional to write you a prescription for a 90-day supply of topiramate instead of a 30-day supply to compare costs. A 3-month supply may be a better value and reduce your trips to the pharmacy. If you have insurance that covers topiramate, ask about discounts for using your plan’s mail-order pharmacy.
GoodRx can easily compare costs at different pharmacies to help you find the best topiramate price in your area.
If you are concerned about the cost of your medication, tell your prescriber. There may be another medication or another version of your medication that better fits your budget, while still adequately treating your condition.
If you have a health savings account (HSA), flexible spending account (FSA), or health reimbursement arrangement (HRA), using those funds to purchase your medication can reduce your out-of-pocket costs through tax savings.
How much you’ll pay for topiramate (Topamax) will depend on what form of the medication you’re prescribed and your daily dose. It will also depend on what pharmacy you choose and where it’s located.
Some health insurance plans may cover the cost of generic topiramate. Brand-name versions of topiramate, such as Topamax, are less likely to be covered by insurance. But you may be able to use coupons from GoodRx or patient assistance programs to help you afford generic or brand-name topiramate.
If you don’t have insurance, you may be able to save on your topiramate prescription by comparing prices at different pharmacies or requesting a larger supply.
National prescription coverage data for each medication was obtained from Managed Markets Insight & Technology (MMIT), reflecting health insurance coverage as of September 2024. The percentage of enrollees in plans that cover each medication was calculated by dividing the number of enrollees covered for the medication within a specific insurance channel (e.g., ACA, Medicare, Medicaid) by the total number of enrollees in all plans within that channel. Similarly, the percentage of enrollees in plans with prior authorization was determined by calculating the proportion of enrollees in plans that require prior authorization for the medication within each channel. The percentage of enrollees in plans with step therapy was calculated as the proportion of enrollees in plans that impose step therapy requirements for the medication in each channel. These estimates, derived from national MMIT coverage data, provide insight into the health insurance coverage landscape for each medication, taking into account restrictions such as prior authorization, step therapy, and quantity limits. The percentages are expressed relative to the total population of enrollees covered by insurance across various channels, including ACA, commercial (excluding ACA) plans, Medicare, and Medicaid (both state and managed Medicaid).
HealthCare.gov. (n.d.). Appealing a health plan decision.
Medicaid.gov. (n.d.). Managed care.
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