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Thyrolar

levothyroxine / liothyronine
Used for Hypothyroidism
Used for Hypothyroidism

Levothyroxine/liothyronine, also known as liotrix, is a combination of thyroid hormones that refills your body's natural hormones. It treats symptoms of low thyroid hormone levels in your body, such as tiredness, weight gain, sensitivity to cold, and goiters, and helps manage thyroid cancer. This medication has been discontinued and is no longer available.

Reviewed by:
reviewer
Cydnee Ng, PharmD
reviewer
Michelle Nguyen, PharmD
Last reviewed on September 17, 2021
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What is Liotrix?

How Liotrix works

Drug Facts

Common BrandsThyrolar (brand no longer available)
Drug ClassTriiodothyronine (T3) / Thyroxine (T4)
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
faqs

Frequently asked questions about Liotrix

What is liotrix?
Liotrix treats low thyroid hormone levels in the body (hypothyroidism) and helps manage thyroid cancer. Since thyroid hormones regulate your metabolism, temperature, heart rate, and other important functions, low hormone levels can cause tiredness, sensitivity to cold, dry skin, weight gain, and slow heart rate. The combination medication contains two types of thyroid hormones, called thyroxine (also known as levothyroxine, or T4) and triiodothyronine (also known as liothyronine, or T3). These thyroid hormones help replace those naturally made by your thyroid gland and relieve symptoms of low hormone levels, including goiter (enlarged thyroid).
Is liotrix still available?
No, liotrix was discontinued in December 2018. The medication is no longer available.
Why was liotrix discontinued?
The manufacturer (Allergen) decided to discontinue liotrix because of business reasons that were not specified. The manufacturer did not discontinue the medication because of concerns about the product's quality or safety or how well it works.
Are there any alternative medications available?
Currently, there are no combination medications specifically containing liothyronine and levothyroxine that are available. However, these ingredients are available as separate medications: liothyronine (Cytomel) and levothyroxine (Synthroid, Levoxyl). There is also a medication called Armour Thyroid (thyroid desiccated) that is a naturally-derived combination of the T3 and T4 thyroid hormones made by your thyroid gland. Ask your provider to see which alternative might be most beneficial for you.
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interactions

Interactions between Liotrix and other drugs

Liotrix may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Liotrix. Please note that only the generic name of each medication is listed below.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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