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Sovaldi

Sovaldi Side Effects

Hope Chang, PharmD, AAHIVPMichelle Nguyen, PharmD
Reviewed by Hope Chang, PharmD, AAHIVP, Michelle Nguyen, PharmD
Last reviewed on May 31, 2021

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Since [[EDITOR|DRUG_DISPLAY_NAME]] is always taken with other medications it is difficult to know what side effects this specific medication causes. Many of these side effects may be caused by other hepatitis C medications, such as ribavirin and peginterferon.

  • Fatigue, tireness (38%)
  • Headache (24%)
  • Nausea (22%)
  • Trouble sleeping, insomnia (15%)
  • Itchy skin (11%)
  • Anemia/low blood count (10%)
  • Irritability (10%)
  • Rash (8%)

Less Common Side Effects

  • Low appetite
  • Muscle pain
  • Weakness
  • Cold and flu symptoms
  • Chills

Source: FDA

The following Sovaldi side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Chills

fever

lower back or side pain

pale skin

ulcers, sores, or white spots in the mouth

unusual tiredness or weakness

Rare

Changes in behavior

discouragement

feeling sad or empty

loss of interest or pleasure

thoughts of killing oneself

trouble concentrating

Incidence not known

Chest pain or discomfort

lightheadedness, dizziness, or fainting

shortness of breath

slow or irregular heartbeat

unusual tiredness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Decreased appetite

diarrhea

difficulty with moving

headache

irritability

lack or loss of strength

muscle aching or cramping

muscle pains or stiffness

nausea

rash or itching skin

trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Hope Chang is a freelance writer and content reviewer for GoodRx. She attended Howard University College of Pharmacy in Washington, D.C. and completed post-graduate residency training at the University of California, Davis Medical Center.
Michelle Nguyen, PharmD, has been a clinical pharmacist for 6 years (and counting). She has a diverse skill set within managed care pharmacy, specifically in the settings of a medical group, pharmacy benefit manager (PBM), and health plan.

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