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Sotyktu

Sotyktu Side Effects

Robert Chad Hakim, PharmD, BCCCPCydnee Ng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Cydnee Ng, PharmD
Last reviewed on March 9, 2026

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Less Common Side Effects

Sotyktu serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reaction: rash, trouble breathing, feeling faint, swelling of the face or throat
  • Serious infection: fever, weakness, chills, trouble breathing, cough, night sweats, diarrhea, stomach pain, burning when you urinate, urinating more or less often
  • Severe muscle damage (rhabdomyolysis): dark brown urine, severe muscle weakness or pain, fever, tiredness
  • Liver damage: nausea, stomach pain, yellowing of the skin or whites of the eyes

Source: Prescribing information

The following Sotyktu side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Acne
  • Pain, redness, or swelling with sores inside the mouth or throat
  • Runny or stuffy nose
  • Sinus pain or pressure around the face or forehead
  • Small, red, pus-filled bumps on skin around hair follicles
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