The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
See Risks and Warnings.
Less Common Side Effects
- Burning sensation on the skin
- Skin irritation
Source: DailyMed
The following Soolantra side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Less common—for the treatment of river blindness (onchocerciasis) only
Eye or eyelid irritation, pain, redness, or swelling
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common—for the treatment of river blindness (onchocerciasis) only
joint or muscle pain
painful and tender glands in neck, armpits, or groin
rapid heartbeat
Less common—for the treatment of river blindness (onchocerciasis) only
Headache
swelling of the face, hands, arms, feet, or legs
Rare—for the treatment of river blindness (onchocerciasis) only
Lightheadedness when getting up from a lying or sitting position
Rare—for the treatment of strongyloidiasis only
Loss of appetite
shaking or trembling
sleepiness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.


