The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Irregular and/or heavy vaginal bleeding (17%)
- Weight gain (5%)
- Acne (5%)
Less Common Side Effects
- Mood changes
- Nausea
- Feeling tired
- Muscle spasms
- Bloating
- Swelling in the hands and feet
- Brownish patch on the face
- Problems tolerating contact lenses
Seasonique serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Heart attack: chest pain, belly discomfort, sweating, nausea, dizziness
- Stroke: sudden numbness or weakness in the arm, leg, or face, confusion, trouble seeing, headache, difficulty walking
- Deep vein thrombosis (blood clot in the leg): leg cramp, swelling, pain, muscle tightness
- Pulmonary embolism (blood clot in the lung): cough, chest pain, trouble breathing, racing heart
- Liver or gallbladder problems: yellowing of the skin or the whites of the eyes, tiredness, pain in the right upper stomach, dark urine
Source: DailyMed
The following Seasonique side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Blood clot—pain, swelling, or warmth in the leg, shortness of breath, chest pain
- Gallbladder problems—severe stomach pain, nausea, vomiting, fever
- Increase in blood pressure
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- New or worsening migraines or headaches
- Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision
- Unusual vaginal discharge, itching, or odor
- Worsening mood, feelings of depression
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Breast pain or tenderness
- Dark patches of skin on the face or other sun-exposed areas
- Irregular menstrual cycles or spotting
- Nausea
- Weight gain
Other Seasonique articles
Other Estrogen / Progestin Combinations side effects articles
- Yaz (jasmiel, lo-zumandimine, loryna, nikki, vestura) side effects
- Prempro side effects
- Ethinyl estradiol/norethindrone side effects
- Activella (abigale, amabelz, estradiol/norethindrone, etyqa, lopreeza, mimvey) side effects
- Loestrin 1/20 (aurovela 1/20, junel 1/20, larin 1/20, microgestin 1/20) side effects
- Cryselle side effects
- Loestrin 21 1.5/30 (aurovela 1.5/30, hailey 1.5/30, junel 1.5/30, larin 1.5/30, microgestin 1.5/30) side effects
- Bijuva side effects
- Azurette side effects
