Tri Sprintec

Tri-Sprintec Side Effects

Reviewed by Sarah Lobello Pearson, PharmD, Allison Gourley, PharmD

Last reviewed on August 25, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Headache or migraine (34%)
Breast changes (tenderness, enlargement) (8%)
Vaginal infection (7%)
Stomach pain (6%)

Less Common Side Effects

Mood changes
Vaginal discharge
Changes in weight

Tri-Sprintec serious side effects

Contact your healthcare provider immediately if you experience any of the following.

Heart attack: chest pain, stomach discomfort, sweating, nausea, dizziness
Stroke: sudden numbness or weakness in the arm, leg, or face, confusion, trouble seeing, headache, difficulty walking
Deep vein thrombosis (blood clot in the leg): leg cramp, swelling, pain, muscle tightness
Pulmonary embolism (blood clot in the lung): cough, chest pain, trouble breathing, racing heart

When do Tri-Sprintec possible side effects begin and end?

Time passed since treatment started:

HHOURS

DDAYS

WWEEKS

MMONTHS

Changes in menstrual bleeding

Headaches

Stomach cramps

Breast pain

Mood changes

Seek immediate medical care if you experience this side effect.

If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following Tri-Sprintec side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

Absent, missed, or irregular menstrual periods

anxiety

change in vision

changes in skin color

chest pain or discomfort

chills

clay-colored stools

constipation

cough

dark urine

diarrhea

dizziness or lightheadedness

fainting

fever

headache

hives or welts

itching skin

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

loss of appetite

medium to heavy, irregular vaginal bleeding between regular monthly periods, which may require the use of a pad or a tampon

nausea

pain or discomfort in the arms, jaw, back, or neck

pain, tenderness, or swelling of the foot or leg

pains in the chest, groin, or legs, especially in the calves of the legs

pounding in the ears

rash

redness of the skin

severe headaches of sudden onset

slow or fast heartbeat

stomach pain

sudden loss of coordination or slurred speech

sudden troubled breathing

sweating

unusual tiredness or weakness

vomiting

vomiting of blood

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Bloating

blotchy spots on the exposed skin

breast enlargement or tenderness

discouragement

feeling sad or empty

irritability

itching of the vagina or outside the genitals

loss of interest or pleasure

pain during sexual intercourse

stomach cramps

thick, white curd-like vaginal discharge without odor or with mild odor