The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Acromegaly
- Diarrhea (36-47%)
- Gallstones (13-38%)
- Stomach pain (25-29%)
- Passing gas (25%)
Carcinoid Tumor and VIPoma
- Nausea (24-41%)
- Stomach pain (10-35%)
- Tiredness (8-32%)
- Headache (16-30%)
- Back pain (8-27%)
- Dizziness (18-20%)
Less Common Side Effects
- Flu-like symptoms
- Constipation
- Headache
- Anemia
- Pain at injection site
- Gallstones
- High blood pressure
- Dizziness
- Joint pain
- Muscle pain
- Changes in blood sugar
- Back pain
- Low thyroid hormone
Sandostatin Lar Depot serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Dangerously low blood sugar: feeling faint, shaking, sweating, dizziness, fast heartbeat, nervousness, anxious, confused, irritable, feeling very hungry
- Dangerously high blood sugar: frequently thirsty, needing to urinate often, tiredness, nausea, vomiting, difficulty breathing, having fruity breath, having dry mouth
- Heart rhythm problems: Chest pounding, fluttering in the chest, difficulty breathing, chest pain, feeling faint or lightheaded
- Swelling of the gallbladder or pancreas: sudden pain in upper right portion of your stomach area, back pain between your shoulder blades, nausea, vomiting, fever, swelling in the belly, fast heartbeat, difficulty breathing
Source: DailyMed
The following Sandostatin Lar Depot side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
depressed mood
dizziness
dry skin and hair
fainting
fast, slow, or irregular heartbeat
feeling cold
hoarseness or husky voice
loss of appetite
muscle cramps and stiffness
severe stomach pain with nausea and vomiting
stomach pain
unusual tiredness or weakness
vomiting
Less common
bladder pain
bloody or cloudy urine
blurred vision
chills
cold sweats
collection of blood under the skin
confusion
cool, pale skin
deep, dark purple bruise
difficult, burning, or painful urination
flushed, dry skin
frequent urge to urinate
fruit-like breath odor
headache
increased hunger
increased thirst
increased urination
itching, pain, redness, or swelling
loss of consciousness
lower back or side pain
nervousness
nightmares
seizures
shakiness
slurred speech
sweating
swelling
trouble breathing
unexplained weight loss
Rare
Black, tarry stools
bleeding gums
blood in vomit
changes in skin color, pain, tenderness, swelling of the foot or leg
chest pain or tightness
coughing up blood
dark urine
decreased urine output
difficulty in breathing or swallowing
difficulty swallowing
dilated neck veins
extreme tiredness or weakness
fast, irregular, pounding, or racing heartbeat or pulse
increased menstrual flow or vaginal bleeding
irregular breathing
itching, pain, redness, swelling, tenderness, or warmth on the skin
light-colored stools
nosebleeds
pain in the groin or genitals
pale skin
paleness or cold feeling in the fingertips and toes
paralysis
pounding in the ears
prolonged bleeding from cuts
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
red or dark brown urine
severe or continuing stomach pain
sharp back pain just below the ribs
swelling of the face, fingers, feet, or lower legs
tingling or pain in the fingers or toes when exposed to cold temperatures
unusual bleeding or bruising
upper right abdominal or stomach pain
yellow eyes and skin
Incidence not known
Blindness
clear or bloody discharge from nipple
decreased vision
delusions of persecution, mistrust, suspiciousness, and/or combativeness
dimpling of the breast skin
gaseous
indigestion
inverted nipple
lump in the breast or under the arm
pain or discomfort in the arms, jaw, back, or neck
pains in the stomach, side, or abdomen, possibly radiating to the back
persistent crusting or scaling of the nipple
pinpoint red spots on the skin
recurrent fever
redness of swelling of the breast
severe constipation
severe cramping
sore on the skin of the breast that does not heal
sores, ulcers, or white spots on the lips or in the mouth
stomach fullness
swollen glands
tearing
weakness of the muscles in your face
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
blurred vision
chills
cold sweats
coma
confusion
cool, pale skin
dizziness
fast heartbeat
feeling of warmth
headache
increased hunger
nervousness
nightmares
redness of the face, neck, arms and occasionally, upper chest
seizures
shakiness
slurred speech
unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Abnormal stool
excess air or gas in the stomach or bowels
full feeling
pain, redness, stinging, swelling, tingling, or burning sensation at the injection site
passing of gas
Less common
Backache
feeling of warmth
joint pain
redness of the face, neck, arms and occasionally, upper chest
Rare
Absent, missed, or irregular menstrual periods
change in vision
difficulty in moving
feeling of constant movement of self or surroundings
hearing loss
itching of the vagina or genital area
joint swelling or redness
loss of vision
memory loss
numbness or tingling of the hands, feet, or face
pain during sexual intercourse
sensation of spinning
stopping of menstrual bleeding
swelling of the breasts or breast soreness in both females and males
thick, white vaginal discharge with no odor or with a mild odor
unexpected or excess milk flow from the breasts
Incidence not known
Decreased interest in sexual intercourse
inability to have or keep an erection
loss in sexual ability, desire, drive, or performance
unexpected or excess milk flow from the breasts
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Other Sandostatin Lar Depot articles
Other Somatostatin Analogues side effects articles
Why trust our experts?

