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Lanreotide

Lanreotide Side Effects

Robert Chad Hakim, PharmD, BCCCPConnie Zheng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Connie Zheng, PharmD
Last reviewed on March 31, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Common side effects reported from people taking [[EDITOR|DRUG_DISPLAY_NAME]] for acromegaly:

  • Diarrhea (up to 73%)
  • Gallstones (up to 27%)
  • Stomach pain (up to 20%)
  • Injection site reactions, such as pain, itching, nodule, skin hardening (up to 17%)
  • Joint pain (up to 10%)

Common side effects reported from people taking [[EDITOR|DRUG_DISPLAY_NAME]] for GEP-NETs:

  • Stomach pain (34%)
  • Muscle pain (19%)
  • Vomiting (19%)
  • Headache (16%)
  • Injection site reactions, such as pain, itching, redness, swelling, rash, bruising/bleeding (15%)
  • High blood sugar (14%)
  • High blood pressure (14%)
  • Gallstones (14%)

Less Common Side Effects

Other side effects reported from people taking [[EDITOR|DRUG_DISPLAY_NAME]] for acromegaly:

  • Nausea
  • Passing gas
  • Low heartbeat
  • High blood pressure
  • Anemia
  • Constipation
  • Vomiting
  • Headache

Other side effects reported from people taking [[EDITOR|DRUG_DISPLAY_NAME]] for GEP-NETs:

  • Dizziness
  • Depression
  • Difficulty breathing

Lanreotide serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Dangerously low blood sugar: feeling faint, shaking, sweating, dizziness, fast heartbeat, nervousness, anxious, confused, irritable, feeling very hungry
  • Dangerously high blood sugar: frequently thirsty, needing to urinate often, tiredness, nausea, vomiting, difficulty breathing, having fruity breath, having dry mouth
  • Low heartbeat: chest pain, dizziness, fatigue, feeling faint
  • High blood pressure: severe headaches, nosebleed, fatigue, confusion, chest pain, difficulty breathing
  • Swelling of the gallbladder or pancreas: sudden pain in upper right portion of your stomach area, back pain between your shoulder blades, nausea, vomiting, fever, swelling in the belly, fast heartbeat, difficulty breathing

Source: DailyMed

The following Lanreotide side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Blurred vision

chest pain or discomfort

dizziness

gaseous abdominal or stomach pain

headache

lightheadedness, dizziness, or fainting

nervousness

pale skin

pounding in the ears

recurrent fever

slow, fast, or irregular heartbeat

stomach fullness

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

yellow eyes or skin

Incidence not known

Bloating

chills

clay-colored stools

confusion

constipation

cough

dark urine

diarrhea

difficulty swallowing

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

fat in the stool

fever

hives, itching, skin rash

indigestion

large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals

loss of appetite

nausea

pains in the stomach, side, or abdomen, possibly radiating to the back

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

severe nausea or vomiting

stomach pain or cramps

sudden loss of weight

sweating

tightness in the chest

unusual drowsiness, dullness, or feeling of sluggishness

vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Difficulty having a bowel movement

difficulty with moving

excess air or gas in the stomach or bowels

feeling of fullness

inflammation, itching, lumps, or pain at the injection site

muscle pain or stiffness

pain in the joints

passing gas

weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Connie Zheng, PharmD, is a drug information pharmacist at GoodRx and a licensed pharmacist in California. She has over 6 years of experience working in independent pharmacies.

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