Reyvow Dosages for Adults: Your GoodRx Guide

Living with migraines can be challenging. These often-unpredictable, sometimes-severe headaches can be debilitating. In addition to causing headaches, migraines can cause nausea, vision changes, and sensitivity to lights and sounds.

One way to manage migraines is by taking medication right when you experience migraine symptoms. If over-the-counter pain relievers don’t work well enough, prescription medications may be an option. Reyvow (lasmiditan) is a prescription-only medication that’s FDA approved to treat migraines in adults.

Here, we’ll take a look at common Reyvow dosages for adults, as well as some tips for how to administer Reyvow.

Promotion disclosure

Reyvow

Avg retail price

$884.36(Save 18.30%)

GoodRx discount

$722.49

Compare all prices

What’s the typical Reyvow dosage for adults?

Reyvow is available in 50 mg and 100 mg oral tablets. The typical Reyvow dosage is 50 mg, 100 mg, or 200 mg taken as a single dose when symptoms of a migraine attack begin. In most cases, prescribers recommend 50 mg or 100 mg per dose to start. They may recommend increasing to 200 mg if these lower doses don’t provide enough relief.

Reyvow is only taken to treat migraines once symptoms start. It’s not a medication you take every day to prevent migraines.

You shouldn’t take more than 1 dose of Reyvow for a single migraine attack. Studies found that taking a second dose of Reyvow for the same migraine attack doesn’t provide additional relief. In fact, only 1 dose of Reyvow should be taken within a 24-hour time frame.

What’s the maximum Reyvow dosage?

The maximum Reyvow dosage is 200 mg per migraine attack.

You shouldn’t take more than 4 doses of Reyvow per month. This means that you shouldn’t use Reyvow to treat more than four migraine attacks per month.

And as mentioned, you should only take 1 dose of Reyvow within a 24-hour time frame, even if you experience more than one migraine during this time.

EXPERT PICKS: WHAT TO READ NEXT

• What to expect: Learn about common Reyvow (lasmiditan) side effects and how to manage them.

• Reyvow vs. Imitrex (sumatriptan): These two medications relieve migraines. But which one is right for you?

• Prescription migraine treatments: Read about other prescription medications that help prevent and treat migraines.

Who may need a lower dosage of Reyvow?

People with certain health conditions, and those who take certain medications, may need to have their Reyvow dosage adjusted or avoid the medication entirely.

Reyvow dosage adjustments for older adults

Adults age 65 or older may be more likely to experience Reyvow side effects, such as dizziness, drowsiness, pins and needles sensations, and blood pressure changes. What’s more, increased dizziness and drowsiness can cause falls, which can result in injury and disability, especially in older adults.

For this reason, your prescriber may recommend starting Reyvow at a lower dose (50 mg) if you’re 65 or older.

Reyvow dosage adjustments for people with liver problems

Reyvow is partially broken down by the liver. So if you have liver disease, your body may have a harder time breaking down Reyvow. This may lead to increased blood levels of Reyvow and a higher risk of side effects.

Reyvow hasn’t been studied in people with severe liver disease. So we can’t say for sure what effects it could have in these cases. For this reason, your prescriber may recommend avoiding Reyvow entirely if you have severe liver problems, since they can’t predict how it will affect you.

Reyvow dosage adjustments for drug interactions

Reyvow interacts with several other medications and substances. Some Reyvow interactions increase the risk of certain side effects, like drowsiness, dizziness, and impaired driving ability. Examples of substances that increase the risk of side effects when combined with Reyvow include alcohol, benzodiazepines, and opioids.

Additionally, combining Reyvow with medications that lower heart rate can make a slowed heart rate more likely. Examples of medications that can have this effect when combined with Reyvow include beta blockers and calcium channel blockers.

Always review your up-to-date medication list with your prescriber or pharmacist before you start a new medication. If you take a medication that interacts with Reyvow, your prescriber may lower the dosage of one or both of the medications.

What should you know about administering Reyvow?

If you’re prescribed Reyvow, keep these tips in mind to help you stay safe and get the most out of the medication:

• Take Reyvow exactly as prescribed. Reyvow is a controlled substance. This means it’s more likely to be habit-forming and lead to misuse than medications that aren’t controlled substances. There’s also restrictions around how it can be prescribed and refilled. Taking Reyow exactly as prescribed helps minimize your risk of dependence and misuse.

• Wait at least 8 hours after taking Reyvow before performing tasks that require mental alertness. Since Reyvow can cause drowsiness and dizziness, the manufacturer recommends waiting this long to do activities like operating machinery or driving. If you can’t wait this long, you shouldn’t take Reyvow. Your prescriber can recommend another migraine medication.

• You can take Reyvow with or without food. You don’t necessarily need to take Reyvow with food. If you experience nausea after taking a dose, however, try taking it with food next time. The tablets should be swallowed whole, so don’t split or cut them.

What should you do if you take too much Reyvow?

Taking too much Reyvow increases your risk of side effects, including extreme drowsiness and dizziness. This is one reason why it’s important to limit your Reyvow usage to 1 dose per migraine (and 1 dose every 24 hours).

Additionally, taking Reyvow more often than recommended can cause rebound headaches. These are headaches that occur due to the overuse of migraine medications.

If you find yourself taking Reyvow more often than what’s recommended, speak to your prescriber. If you’re having frequent migraines, they may recommend a preventative migraine medication. Or they may recommend an alternative medication for migraine attacks.

If you think that you’ve taken too much Reyvow, you may need to be treated in a hospital. If your symptoms feel severe, seek emergency care by calling 911, or call Poison Control at 1-800-222-1222.

Why trust our experts?

Written by:

Nicole E. Cieri-Hutcherson, PharmD, BCPS, NCMP

Nicole E. Cieri-Hutcherson, PharmD, BCPS, NCMP, has over a decade of experience as a pharmacist, professor, and researcher. She was a full-time clinical professor in the pharmacy practice department at D’Youville School of Pharmacy before subsequently joining the faculty of the pharmacy practice department at the University at Buffalo School of Pharmacy and Pharmaceutical Sciences.

Edited by:

Amy B. Gragnolati, PharmD, BCPS

Amy Gragnolati, PharmD, BCPS, is a pharmacy editor for GoodRx. Amy currently holds her pharmacist license in Georgia and California.

Reviewed by:

Christina Aungst, PharmD

Christina Aungst, PharmD, is a pharmacy editor for GoodRx. She began writing for GoodRx Health in 2019, transitioning from freelance writer to editor in 2021.

Our editorial standards

Meet our experts