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Primidone

Primidone Dosage

Robert Chad Hakim, PharmD, BCCCPCydnee Ng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Cydnee Ng, PharmD
Last reviewed on December 4, 2025

The average cost for 90 tablets of 50mg of Primidone is $16.78 with a free GoodRx coupon. This is 62.99% off the average retail price of $45.34.

tabletTablet

Dosage

Quantity

Price as low as

Price per unit

50mg

90 tablets

$16.78

$0.19

250mg

90 tablets

$13.79

$0.15

125mg

90 tablets

$48.52

$0.54

Typical dosage for Primidone

  • Adults and children ages 8 years and older

    • Days 1 to 3: The typical dose is 100 mg to 125 mg by mouth at bedtime.
    • Days 4 to 6: The typical dose is 100 mg to 125 mg by mouth twice a day.
    • Days 7 to 9: The typical dose is 100 mg to 125 mg by mouth three times a day.
    • Day 10 and thereafter: The typical dose is 250 mg by mouth three or four times a day. Some people might need a higher dose, but the maximum dose is 500 mg taken four times a day.
  • Children under 8 years old

    • Days 1 to 3: The typical dose is 50 mg by mouth at bedtime.
    • Days 4 to 6: The typical dose is 50 mg by mouth twice a day.
    • Days 7 to 9: The typical dose is 100 mg by mouth twice a day.
    • Day 10 and thereafter: The typical maintenance dose is 125 mg to 250 mg by mouth three times a day. Another option is based on weight: 10 mg/kg to 25 mg/kg per day, split into multiple doses during the day.
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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Cydnee Ng, PharmD
Reviewed by:
Cydnee Ng, PharmD
Cydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.

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