Potassium Chloride vs. Potassium Citrate: What’s the Best Potassium Supplement?
Explore the differences between potassium chloride and potassium citrate to find the best potassium supplement for your needs.
potassium chloride
Used for Hypokalemia
Used for Hypokalemia
Potassium chloride is a prescription medication used to prevent and treat low blood potassium levels (hypokalemia). It's also known by its brand names, Klor-Con, Klor-Con M, and Klor-Con Sprinkle. Oral potassium chloride is available in many forms, including capsules, tablets, and oral solutions. This medication is taken by mouth, typically multiple times a day. Some of the most common side effects of oral potassium chloride include nausea, vomiting, and stomach upset. Oral potassium chloride is also available over the counter in lower doses as a supplement.
What is Oral potassium chloride?
What is Oral potassium chloride used for?
- Prevention and treatment of low blood potassium levels (hypokalemia)
How Oral potassium chloride works
Oral potassium chloride is a potassium salt, or supplement, used to raise your blood potassium levels when they're too low. Potassium is essential for heart, nerve, and muscle health as well as for other important processes in the body to work properly.
Drug facts
| Common Brands | Klor-Con, Klor-Con M, Klor-Con Sprinkle, Pokonza |
|---|---|
| Drug Class | Dietary supplement |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | Lower-cost generic available |
| Availability | Prescription or over-the-counter |
More on Oral potassium chloride essentials
Side effects of Oral potassium chloride
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Nausea
- Vomiting
- Passing gas
- Stomach pain or discomfort
- Diarrhea
Oral potassium chloride serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Dangerously high potassium: tiredness, weakness, muscle cramps or pain, chest pain, unusual heartbeat, trouble breathing
- Injury to the stomach or intestines: vomiting, stomach pain, bloating, black-colored or tarry stools
When do Oral potassium chloride possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Nausea
Stomach discomfort
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.
The following Oral potassium chloride side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Stop taking this medicine and check with your doctor immediately if any of the following side effects occur:
Less common
Confusion
irregular or slow heartbeat
numbness or tingling in hands, feet, or lips
shortness of breath or difficult breathing
unexplained anxiety
unusual tiredness or weakness
weakness or heaviness of legs
Check with your doctor as soon as possible if any of the following side effects occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Sometimes you may see what appears to be a whole tablet in the stool after taking certain extended-release potassium chloride tablets. This is to be expected. Your body has absorbed the potassium from the tablet and the shell is then expelled.
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Get your GoodRx coupon
$251.66
GoodRx discount
$31.75
Pros and cons of Oral potassium chloride
Pros
- Works well to raise potassium levels
- Available in many different forms (e.g., tablets, capsules, powder, solution, injection)
- Available as a lower-cost generic medication
Cons
- Can cause stomach upset
- Taken multiple times a day
- Requires regular blood draws to monitor potassium levels
Pharmacist tips for Oral potassium chloride
- Make sure to mark your calendar with your appointments to see your provider and to get any blood work done when you take oral potassium chloride. Your provider might order tests (e.g., potassium level, kidney function) during treatment and might change your dose of oral potassium chloride based on your lab results.
- Take each oral potassium chloride dose with a meal and full glass of water or other liquid to lower the chances of stomach upset. Don't take oral potassium chloride on an empty stomach.
- Ask your provider or dietician to see if you're already getting enough potassium through foods based on your diet. If so, your provider might lower your dose of oral potassium chloride or ask you to stop taking it altogether.
- Make sure your provider and pharmacist know about all of your other medications, especially if you take other medications that can change potassium levels.
- Tell your provider if you take diuretics (water pills) like furosemide (Lasix) because they can lower potassium levels. If so, your provider will most likely need to make changes to your dose of oral potassium chloride if you stop taking your water pills.
- Don't take non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin), while taking oral potassium chloride unless your provider specifically said it's safe for you to do so. This is because taking NSAIDs and oral potassium chloride together can cause your potassium level to get too high.
More tips on how to take oral potassium chloride:
- If you're taking potassium chloride (Klor-Con) extended-release tablets, swallow the tablets whole with a full glass of water or meal to lower your risk of stomach upset. Don't crush, chew, or suck on it.
- If you're taking potassium chloride (Klor-Con M) extended-release tablets (not Klor-Con), you can break the tablet in half and swallow each half separately or dissolve the tablet in water. Ask your pharmacist for instructions on how to do this.
- If you're taking potassium chloride (Klor-Con Sprinkle) extended-release capsules, you can swallow the capsule whole, or open the capsule and sprinkle the medication onto soft food like applesauce or pudding. The soft food shouldn't be hot, and should be easy to swallow without chewing. Swallow the dose right after putting it on the food, without chewing. Drink a glass of water or juice afterwards to wash down all of the medication.
- If you're taking the powder packets or oral solution, make sure to mix the dose with at least a half-cup (4 ounces) of water. Each packet contains 20 mEq, but the solution form comes in two different concentrations so make sure to double-check that you're taking the right amount for your dose.
Risks and warnings for Oral potassium chloride
Oral potassium chloride can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk of high blood potassium levels
Risk factors: Taking other medications that can raise potassium levels | Kidney problems
Only take oral potassium chloride as directed by your provider. Taking too much oral potassium chloride can cause high blood potassium levels. Your risk is higher if you're taking other medications that can raise potassium, like spironolactone (Aldactone) or lisinopril (Zestril). If you experience signs of high potassium levels, such as nausea, or muscle weakness, tell your healthcare provider right away. If left untreated, high potassium levels can be dangerous.
Stomach or intestinal injury
Risk factors: Taking a pill form of oral potassium chloride | Difficulty swallowing or slow intestinal movement
Oral potassium supplements can cause stomach-related side effects because they can be irritating to the stomach and intestines. Rarely, this can lead to ulcers, tearing, bleeding, and other serious internal injury. If you've difficulty swallowing or have a condition that causes slow movement in the intestines, your provider will recommend the liquid form of oral potassium chloride over the pill form. This is because the liquid form is less likely to cause stomach irritation. If you experience severe vomiting, stomach pain, bloating (which might be a symptom of blockage), or black-colored stools (a possible symptom of bleeding bleeding), stop taking oral potassium chloride and contact your provider right away.
Oral potassium chloride dosage
The average cost for 30 packets of 20meq of Oral potassium chloride is $34.01 with a free GoodRx coupon. This is 88.08% off the average retail price of $285.22.
Interactions between Oral potassium chloride and other drugs
Oral potassium chloride may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Oral potassium chloride. Please note that only the generic name of each medication is listed below.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these dietary supplements, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using dietary supplements in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with dietary supplements in this class or change some of the other medicines you take.
- Amantadine
- Atropine
- Belladonna
- Belladonna Alkaloids
- Benztropine
- Bepridil
- Biperiden
- Burosumab-twza
- Cisapride
- Clidinium
- Darifenacin
- Dicyclomine
- Dronedarone
- Eplerenone
- Fesoterodine
- Glycopyrrolate
- Hyoscyamine
- Mesoridazine
- Methscopolamine
- Oxybutynin
- Pimozide
- Piperaquine
- Procyclidine
- Saquinavir
- Scopolamine
- Solifenacin
- Sparfloxacin
- Terfenadine
- Thioridazine
- Tolterodine
- Trihexyphenidyl
- Trospium
- Ziprasidone
Using dietary supplements in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Alacepril
- Alfuzosin
- Amiloride
- Amiodarone
- Amisulpride
- Amitriptyline
- Amoxapine
- Anagrelide
- Apomorphine
- Aripiprazole
- Aripiprazole Lauroxil
- Arsenic Trioxide
- Asenapine
- Astemizole
- Azilsartan
- Azilsartan Medoxomil
- Azithromycin
- Bedaquiline
- Benazepril
- Buprenorphine
- Buserelin
- Candesartan
- Canrenoate
- Canrenone
- Captopril
- Ceritinib
- Chloroquine
- Chlorpromazine
- Cilazapril
- Ciprofloxacin
- Citalopram
- Clarithromycin
- Clofazimine
- Clomipramine
- Clozapine
- Crizotinib
- Cyclobenzaprine
- Cyclosporine
- Dabrafenib
- Dasatinib
- Degarelix
- Delamanid
- Delapril
- Desipramine
- Deslorelin
- Deutetrabenazine
- Digoxin
- Disopyramide
- Dofetilide
- Dolasetron
- Domperidone
- Donepezil
- Droperidol
- Efavirenz
- Enalapril
- Enalaprilat
- Encorafenib
- Entrectinib
- Eplerenone
- Eprosartan
- Erdafitinib
- Erythromycin
- Escitalopram
- Fingolimod
- Flecainide
- Fluconazole
- Fluoxetine
- Formoterol
- Foscarnet
- Fosinopril
- Fostemsavir
- Gatifloxacin
- Gemifloxacin
- Glasdegib
- Gonadorelin
- Goserelin
- Granisetron
- Halofantrine
- Haloperidol
- Histrelin
- Hydroxychloroquine
- Hydroxyzine
- Ibutilide
- Iloperidone
- Imidapril
- Imipramine
- Indomethacin
- Inotuzumab Ozogamicin
- Irbesartan
- Ivabradine
- Ivosidenib
- Ketoconazole
- Lapatinib
- Lefamulin
- Lenvatinib
- Levofloxacin
- Lisinopril
- Lofexidine
- Lopinavir
- Losartan
- Lumefantrine
- Macimorelin
- Mefloquine
- Methadone
- Metronidazole
- Mifepristone
- Mirtazapine
- Moexipril
- Moxifloxacin
- Nafarelin
- Nilotinib
- Norfloxacin
- Nortriptyline
- Octreotide
- Ofloxacin
- Olmesartan
- Ondansetron
- Osilodrostat
- Osimertinib
- Oxaliplatin
- Ozanimod
- Paliperidone
- Panobinostat
- Pasireotide
- Pazopanib
- Pentopril
- Perindopril
- Pimavanserin
- Pitolisant
- Ponesimod
- Posaconazole
- Procainamide
- Prochlorperazine
- Promethazine
- Propafenone
- Protriptyline
- Quetiapine
- Quinapril
- Quinidine
- Quinine
- Ramipril
- Ranolazine
- Ribociclib
- Selpercatinib
- Sertraline
- Sevoflurane
- Siponimod
- Solifenacin
- Sorafenib
- Sotalol
- Spirapril
- Spironolactone
- Sulpiride
- Sunitinib
- Tacrolimus
- Telavancin
- Telithromycin
- Telmisartan
- Temocapril
- Tetrabenazine
- Toremifene
- Trandolapril
- Trazodone
- Triamterene
- Triclabendazole
- Trifluoperazine
- Trimipramine
- Triptorelin
- Valsartan
- Vandetanib
- Vardenafil
- Vemurafenib
- Vinflunine
- Voclosporin
- Voriconazole
- Zofenopril
- Zuclopenthixol
How much does Oral potassium chloride cost?
To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
Oral potassium chloride contraindications
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Oral potassium chloride will not be safe for you to take.
- Currently taking amiloride (Midamor) or triamterene (Dyrenium)
What are alternatives to Oral potassium chloride?
There are a number of medications that your doctor can prescribe in place of Oral potassium chloride. Compare a few possible alternatives below.
News about Oral potassium chloride
Oral potassium chloride images
