Pneumovax 23 is a inactivated polysaccharide vaccine. It protects you from a bacteria called Streptococcus pneumoniae that can cause many types of infections, including pneumonia and meningitis. Pneumovax 23 is typically given as a shot into the muscle by a healthcare professional (HCP). It's mainly given to older adults. But sometimes, HCPs might recommend it to children and younger adults with certain health conditions. Side effects of this vaccine include injection-site pain and redness, muscle pain, and headache.
Prevention of pneumococcal disease (infections caused by pneumococcus)
Pneumovax 23 is a vaccine that protects you against pneumococcal disease, an infection caused by the bacteria Streptococcus pneumoniae (also known as "pneumococcus"). This bacteria can infect many parts of the body and cause serious problems.
Pneumovax 23 is an inactivated vaccine that helps your body's immune system make antibodies that will attack the bacteria if it ever infects you.
Source: DailyMed
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
Works well to prevent severe pneumococcal disease
Protects against 23 types of pneumococcal bacteria
The vial stopper, syringe plunger stopper, and syringe cap don't contain natural rubber latex.
Can only be given as an injection
Brand name only
Must be given by a healthcare professional
Pneumovax 23 is typically only one injection into the muscle or under the skin of your shoulder or mid-thigh.
Wait until you're healthy to get Pneumovax 23. This will help make sure your immune system protects you as best as it can. If you have a mild sickness, such as a cold, you can still get Pneumovax 23. But if you feel moderately to severely sick, wait until you recover before getting this vaccine.
Make sure to keep a record of all your immunizations and show it to your healthcare professional before receiving any vaccine, including Pneumovax 23. This is helpful for your care team in figuring out what vaccines you need.
Read the vaccine information statement for more information on Pneumovax 23.
The most common side effects of Pneumovax 23 are typically mild and last 1 or 2 days. But if they last longer and are severe, contact your primary care provider.
If you develop a severe reaction to Pneumovax 23, you or your healthcare team can report it to the vaccine adverse event reporting system (VAERS) website or by calling 1-800-822-7967.
Pneumovax 23 can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
As with any vaccine, there's a small chance that you might have a severe allergic reaction to Pneumovax 23. Your healthcare professional might ask you to stay at the pharmacy or clinic for a short period of time after you've received your vaccine to make sure you can get proper care in case of a serious allergic reaction. Sometimes, these reactions can happen after you've already left the clinic. Get medical help right away if you notice symptoms of a severe allergic reaction, such as feeling faint, swelling of the face, closing of the throat, difficulty breathing, hives or rash, dizziness, shaking, nausea, or chest pain.
Risk factors: Current moderate-to-severe illness | Medical conditions or medications that weaken the immune system | Cerebrospinal fluid leakage
Pneumovax 23 might not work as well in people with certain medical conditions. If you have any of the risk factors listed above, don't get Pneumovax 23 until you talk to your primary care provider first.
Pneumovax 23 doesn't replace the need for using antibiotics (treatment or prevention) against pneumococcal infections. It's important that you take your antibiotics exactly as prescribed, whether it's for preventing or treating an infection from pneumococcus, even if you receive Pneumovax 23.
The dose is 1 injection into the muscle or under the skin of your shoulder or the outside of your mid-thigh. Depending on your age and medical conditions, you might need a second dose of Pneumovax 23, which is typically given at least 5 years after the first dose.
Prevention of pneumococcal disease (infections caused by pneumococcus)
Prevention of pneumococcal disease (infections caused by pneumococcus) in people 6 weeks and older
Prevention of ear infections caused by pneumococcus in children 6 weeks to 5 years old
Prevention of pneumococcal infections in people 6 weeks of age and older
Prevention of pneumococcal ear infections in children between 6 weeks and 5 years of age
Prevention of pneumococcal pneumonia in adults 18 years and older
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Centers for Disease Control and Prevention. (n.d.). Pneumococcal disease.
Centers for Disease Control and Prevention. (2019). Pneumococcal polysaccharide VIS.
Centers for Disease Control and Prevention. (2023). Pneumococcal vaccines.
Centers for Disease Control and Prevention. (2023). Pneumococcal vaccine timing for adults.
Centers for Disease Control and Prevention. (2024). Pneumococcal vaccination.
Merck Sharp & Dohme LLC. (2023). Pneumovax 23- pneumococcal vaccine polyvalent injection, solution [package insert]. DailyMed.
World Health Organization. (2020). How do vaccines work?
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