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Pimozide

Pimozide Side Effects

Allison Gourley, PharmDDaisy Chau, PharmD
Reviewed by Allison Gourley, PharmD, Daisy Chau, PharmD
Last reviewed on September 23, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Adults:

  • Sleepiness (14%)
  • Inability to move muscles on your own (8%)
  • Restlessness (8%)
  • Drowsiness (7%)
  • Dry mouth (5%)
  • Behavior problems (5%)

Children:

  • Sleepiness (28%)
  • Behavior problems (28%)
  • Weakness (25%)
  • Headache (22%)
  • Drooling (14%)

Less Common Side Effects

  • Constipation
  • Diarrhea
  • Muscle tightness
  • Trouble sleeping
  • Vision changes
  • Erectile dysfunction
  • Trouble swallowing
  • Muscle pain
  • Rash

Pimozide serious side effects

Contact your healthcare provider immediately if you experience any of the following.

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Source: DailyMed

The following Pimozide side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Difficulty with speaking

dizziness or fainting

fast or irregular heartbeat

lack of facial expression

loss of balance control

mood or behavior changes

restlessness or need to keep moving

shuffling walk

slowed movements

stiffness of the arms and legs

swelling or soreness of the breasts (less common in males)

trembling and shaking of the fingers and hands

unusual secretion of milk (rare in males)

Less common or rare

Difficulty with swallowing

inability to move the eyes

increased blinking or spasms of the eyelid

lip smacking or puckering

menstrual changes

muscle spasms, especially of the face, neck, or back

puffing of the cheeks

rapid or worm-like movements of the tongue

skin rash and itching

sore throat and fever

swelling of the face

uncontrolled chewing movements

uncontrolled movements of the neck, trunk, arms, or legs, including twisting movements

unusual bleeding or bruising

unusual facial expressions or body positions

yellow eyes or skin

Rare

Convulsions (seizures)

difficult or unusually fast breathing

fast heartbeat or irregular pulse

fever (high)

high or low (irregular) blood pressure

increased sweating

loss of bladder control

muscle stiffness (severe)

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Coma

dizziness (severe)

muscle trembling, jerking, or stiffness (severe)

troubled breathing (severe)

uncontrolled movements (severe)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Blurred vision or other vision problems

constipation

dizziness, lightheadedness, or fainting when getting up from a lying or sitting position

drowsiness

dryness of the mouth

skin discoloration

Less common

Decreased sexual ability

diarrhea

headache

loss of appetite and weight

mental depression

nausea and vomiting

tiredness or weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.
Daisy Chau, PharmD
Reviewed by:
Daisy Chau, PharmD
Daisy Chau, PharmD, is the drug information pharmacist manager at GoodRx. She is licensed in California and has more than 6 years of experience working as a pharmacist in drug information.

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