The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Drowsiness
- Extrapyramidal symptoms (movement problems, such as shakiness, stiffness, excess saliva, and loss of facial expression)
- Restless muscles (akathisia)
Less Common Side Effects
- Dizziness
- Feeling faint
- Sleepiness or trouble sleeping
- Confusion
- Trouble swallowing or breathing
- Agitation (distress)
- Slurred speech
- Hair loss
- Dry mouth
- Nausea
Loxapine serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Neuroleptic malignant syndrome (NMS): high fever, muscle stiffness, confusion, sweating, changes in pulse, heart rate, and blood pressure
- Uncontrollable muscle movements of the face, tongue, or other body parts: sticking out your tongue, puffing out your cheeks, puckering your mouth, lip smacking, chewing, shaking in your arms and legs
- Serious infection (from low blood cell count): fever, weakness, fatigue, sore throat, cough, body aches, chills
- Seizures
Source: DailyMed
The following Loxapine side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Difficulty with speaking or swallowing
lip smacking or puckering
loss of balance control
mask-like face
puffing of the cheeks
rapid or fine, worm-like movements of the tongue
restlessness or desire to keep moving
shuffling walk
slowed movements
stiffness of the arms and legs
trembling and shaking of the fingers and hands
uncontrolled chewing movements
uncontrolled movements of the arms or legs
Less common
Constipation (severe)
difficult urination
inability to move the eyes
muscle spasms, especially of the neck and back
skin rash
twisting movements of the body
Rare
Difficult or fast breathing
fast heartbeat or irregular pulse
fever (high)
high or low blood pressure
increased blinking or spasms of the eyelid
increased sweating
loss of bladder control
muscle stiffness (severe)
seizures
sore throat and fever
uncontrolled twisting movements of the neck, trunk, arms, or legs
unusual bleeding or bruising
unusual facial expressions or body positions
unusual tiredness or weakness
unusually pale skin
yellow eyes or skin
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Dizziness, faintness, or lightheadedness when suddenly getting up from a lying or sitting position
drowsiness (severe)
irregular, fast or slow, or shallow breathing
loss of consciousness
muscle trembling, jerking, stiffness, or uncontrolled movements (severe)
pale or blue lips, fingernails, or skin
troubled breathing (severe)
unusual tiredness or weakness (severe)
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Blurred vision
confusion
dizziness, lightheadedness, or fainting
drowsiness
dryness of the mouth
Less common
Constipation (mild)
decreased sexual ability
enlargement of the breasts (males and females)
headache
increased sensitivity of the skin to sunlight
missing menstrual periods
nausea or vomiting
trouble with sleeping
unusual secretion of milk
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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