The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Trouble sleeping (up to 16%)
- Sleepiness (up to 15%)
- Movement problems (up to 12%)
- Restlessness (not being able to sit still, up to 11%)
- Dizziness (up to 7%)
- Constipation (up to 7%)
- Vomiting (up to 7%)
- Mouth numbness (up to 7%)
*Note: Side effects listed above were reported by adults with schizophrenia. Similar side effects are seen in adults and children with bipolar disorder.
Less Common Side Effects
- Dry mouth
- Salivating more
- Tiredness (fatigue)
- Feeling irritable
- Weight gain
- Bigger appetite
- Stomach discomfort
- High blood pressure
Asenapine serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Depression or thoughts of self-harm
- Seizures
- Neuroleptic malignant syndrome: high fever, sweating, confusion, stiffness, changing blood pressure
- Serious allergic reaction: rash, hives, trouble breathing, swelling of the face, tongue, or throat
- Changes in heartbeat
Source: DailyMed
More on Asenapine side effects
The following Asenapine side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Abnormal or decreased touch sensation
inability to move the eyes
inability to sit still
increase in body movements
increased blinking or spasms of the eyelid
lip smacking or puckering
need to keep moving
puffing of the cheeks
rapid or worm-like movements of the tongue
restlessness
shakiness in the legs, arms, hands, or feet
sticking out of tongue
trembling or shaking of the hands or feet
trouble with breathing, speaking, or swallowing
twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
uncontrolled chewing movements
uncontrolled twisting movements of the neck, trunk, arms, or legs
unusual facial expressions
weakness of the arms and legs
Less common
Blurred vision
dizziness
headache
nervousness
pounding in the ears
slow or fast heartbeat
Rare
Black, tarry stools
bleeding gums
blood in the urine or stools
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
changes in patterns and rhythms of speech
coma
confusion
convulsions
decreased urine output
fast, pounding, or irregular heartbeat or pulse
increased thirst
muscle pain or cramps
nausea or vomiting
pale skin
pinpoint red spots on the skin
slurred speech
swelling of the face, ankles, or hands
troubled breathing with exertion
unusual bleeding or bruising
unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
sleepiness or unusual drowsiness
trouble sleeping
unusually deep sleep
unusually long duration of sleep
Less common
Acid or sour stomach
belching
difficulty with moving
fear or nervousness
increased appetite
increased watering of the mouth
increased weight
indigestion
irritability
muscle pain or stiffness
pain in the arms or legs
pain in the joints
stomach discomfort, upset, or pain
toothache
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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