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Meloxicam for Cats: A Medication for Pain Relief

Sarah J. Wooten, DVM, CVJGhanasyam Bey, DVM
Updated on January 8, 2025

Key takeaways:

  • Meloxicam (Metacam) is a nonsteroidal anti-inflammatory drug (NSAID) that is sometimes used to manage acute pain in cats. 

  • The only FDA-approved form of meloxicam for cats is the injectable form. All oral forms of meloxicam are used off-label (and with caution) for cats.

  • Even when given to healthy cats, meloxicam should be used with caution because long-term use can cause kidney issues.

A man is enjoying time with his cat at home.
Koh Sze Kiat/E+ via Getty Images

While cats don’t tend to show pain the way that humans do, they still experience it — just like their owners. Helping your cat manage pain can be an important part of caring for them. 

Many medications can treat pain and inflammation in dogs, but the same is not true of cats. Meloxicam (Metacam) is one of the few medications that can be used to manage pain in cats. But it is typically only recommended for short-term use. 

Meloxicam for cats at a glance

Common names

Meloxicam (Metacam)

What it treats

Pain and inflammation related to surgery or arthritis (in some cases)

How it comes (forms)

Injection, pills, and liquid

Dosage

0.05 mg/kg of body weight every 1, 2, or 3 days as determined by your veterinarian

Common side effects

Digestive issues like vomiting, soft stool, and poor appetite

Cost

$8-$18 for 30 tablets or $46 for oral liquid (15 mL) 

What is meloxicam for cats, and how does it work?

Meloxicam for cats is a nonsteroidal anti-inflammatory drug (NSAID). NSAIDs manage pain by altering a cat’s body chemicals.

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When a part of a cat’s body is injured, damaged tissues release chemical messengers called prostaglandins. Prostaglandins cause swelling and also increase the pain signals coming from nerves around the injury. Meloxicam blocks the chemical that creates prostaglandins, which reduces swelling and pain. 

What is meloxicam used for in cats?

Meloxicam is used to relieve pain and inflammation in cats. It is often given as a single injection before surgery to manage pain associated with the procedure.

Only a single dose of the injectable form of meloxicam is FDA approved for use in cats. Any other use of meloxicam, whether oral or injectable, is considered off-label by the FDA.

In addition, the FDA requires meloxicam for cats to come with a boxed warning. This means the label includes a warning about the association between repeated doses of meloxicam and kidney failure in cats.

As mentioned, there are a limited number of medications available for treating chronic pain in cats. Therefore, some veterinarians prescribe meloxicam long term to certain cats for chronic pain. But this is only done very rarely and by licensed veterinarians.

How is meloxicam given to cats, and what is the standard dosage?

Cats receive a single injection of meloxicam to manage pain and inflammation from surgery. The injection is usually given by your cat’s veterinarian at a clinic or hospital.

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If your veterinarian decides your cat should get meloxicam for arthritis, they will give your cat the lowest dose possible. This can help reduce the likelihood of serious side effects like kidney failure. 

Oral meloxicam dosage

The dosage for long-term meloxicam in cats is usually 0.05 mg/kg of body weight once a day. Or your veterinarian may recommend giving your cat a lower dose once every 2 or 3 days. If your cat doesn’t seem to have less pain after 14 days, your vet may have you stop giving them meloxicam.

Meloxicam is available in brand-name (Metacam) and generic formulations. It comes as a tablet, tasty liquid, or an oral spray. But these oral forms of Meloxicam are not FDA approved for use in cats. You must thoroughly shake meloxicam oral liquid before use and carefully measure it before giving it to your cat.

Cats who take meloxicam on a long-term basis need to have their blood work checked every 6 months to monitor their kidney health.

What should you do if your cat misses a dose of meloxicam?

If your cat misses a dose of meloxicam, give them the missed dose as soon as possible. 

If it is close to when their next dose is due, skip the missed dose. Then, give your cat the next dose of meloxicam at the regularly scheduled time. 

Never give your cat two doses of meloxicam within a 24-hour period.

What are the common side effects of meloxicam in cats?

Healthy cats can generally take meloxicam safely. The most common side effects of meloxicam reported in cats are:


You can give meloxicam with food to reduce these side effects. If that doesn’t help, contact your veterinarian for advice. 

What are the most serious risks of meloxicam for cats?

Meloxicam for cats can be associated with serious side effects, including:

  • Kidney failure

  • Liver problems

  • Ulcers

  • Severe vomiting

  • Diarrhea

  • Gastrointestinal bleeding, which shows up as bloody or black, tarry stool

  • Less or more urination

  • Pale gums

  • Yellowing of the gums, skin, or whites of the eyes

  • Weakness and incoordination

  • Seizures

If you notice or suspect any of these side effects, stop giving your cat meloxicam. Then, contact your veterinarian or an emergency pet hospital right away.

Does meloxicam interact with any other cat medications?

Don’t give meloxicam at the same time as other NSAIDs. If your cat already takes an NSAID or any other prescription medications or supplements, let your veterinarian know. 

In addition, cats that receive any type of steroid like prednisolone — including an oral, injectable, or topical form — should not be given meloxicam. 

The bottom line

Meloxicam (Metacam) is a nonsteroidal anti-inflammatory drug (NSAID) that can be used to reduce acute pain and inflammation in cats. Meloxicam is also sometimes prescribed off-label for cats to manage chronic pain from arthritis. However, cats that take meloxicam on a long-term basis have a higher risk of serious side effects like kidney failure. 

Always give meloxicam to cats under the guidance of a licensed veterinarian.

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Why trust our experts?

Sarah J. Wooten, DVM, CVJ
Dr. Sarah Wooten, DVM, CVJ, is a well-known international influencer in the veterinary and animal healthcare spaces. She has 16 years of experience in private practice and more than 15 years experience in veterinary media work.
Renée Fabian, MA
Renée Fabian is the senior pet health editor at GoodRx. She’s worked for nearly 10 years as a journalist and editor across a wide range of health and well-being topics.
Ghanasyam Bey, DVM
Reviewed by:
Ghanasyam Bey, DVM
Ghanasyam Bey, DVM, is from Cleveland, Ohio, and attended Princeton University for undergraduate studies. After a year of biology research at Duke University, he attended Ohio State College of Veterinary Medicine.

References

American Association of Feline Practitioners. (n.d.). Metacam statement

Boehringer Ingelheim Animal Health USA Inc. (2023). Metacam® (meloxicam) [package insert].

View All References (5)

Brooks, W. (2019). Meloxicam (Metacam). Veterinary Partner. 

Plumb’s Veterinary Medication Guides. (2020). Meloxicam. Brief Media.

Taylor, S., et al. (2024). 2024 ISFM and AAFP consensus guidelines on the long-term use of NSAIDs in cats. Journal of Feline Medicine and Surgery.

U.S. Food and Drug Administration. (2022). Get the facts about pain relievers for pets: Nonsteroidal anti-inflammatory drugs (NSAIDs).

U.S. Food and Drug Administration. (2023). Information about the boxed warning on meloxicam labels regarding safety risks in cats

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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