provider image
Welcome! You’re in GoodRx for healthcare professionals. Now, you’ll enjoy a streamlined experience created specifically for healthcare professionals.
Skip to main content
HomePet HealthCat Health

Amoxicillin for Cats: This Antibiotic Works for Certain Bacterial Infections

Sarah J. Wooten, DVM, CVJGhanasyam Bey, DVM
Updated on December 18, 2024

Key takeaways:

  • Amoxicillin is an FDA-approved antibiotic that is used to treat a variety of bacterial infections in cats.

  • Amoxicillin is typically prescribed to cats as an oral suspension that must be shaken before use and stored in the fridge.

  • Like all antibiotics, the most common side effect of amoxicillin is stomach problems.

A cat gets a checkup at the vet.
shironosov/iStock via Getty Images Plus

If your cat has been diagnosed with a bacterial infection, they may be prescribed an antibiotic called amoxicillin. Vets commonly prescribe amoxicillin to cats to treat a variety of bacterial infections. When used appropriately, it generally works well and is safe, with a low risk of side effects.

Amoxicillin for cats at a glance

Common brand names

Amoxicillin (Amoxi-Drops, Amoxi-Tabs, Bimox, Amoxil, Trimox, Moxatag)

What it treats

Bacterial infections

How it comes (forms)

Tablets, capsules, liquid suspension, and injection (typically for veterinary use only)

Standard dosage

Based on your cat’s weight and form of medication; usually 10 mg/kg to 25 mg/kg of body weight every 12 hours

Common side effects

Diarrhea, vomiting, loss of appetite, allergic reactions

Cost

$10 for 15 mL oral liquid

What is amoxicillin for cats, and how does it work?

Amoxicillin is an antibiotic that is part of the penicillin family. It kills bacteria by weakening its cell wall, which causes the bacteria to die.

Amoxicillin only works against certain types of bacteria that lack an enzyme called beta-lactamase. Bacteria that have the beta-lactamase enzyme are resistant to amoxicillin. 

ADVERTISEMENT

Pay less for pet prescriptions with GoodRx for Pets

Save up to 80% on medications for dogs, cats, and other pets.

Pets Campaign Native Ad - Non holiday image 2024

Amoxicillin may be combined with clavulanate potassium or clavulanic acid (Clavamox). This can increase the antibiotic’s effectiveness against bacteria with the beta-lactamase enzyme.

What is amoxicillin used for in cats?

Amoxicillin is FDA approved for a variety of bacterial infections in cats. It is most commonly prescribed to cats for bacterial infections that are: 

It may also be prescribed for: 

  • Dental infections

  • Bite wounds

  • Liver infections

  • Some gastrointestinal bacterial infections

How is amoxicillin given to cats, and what’s the standard dosage?

The amoxicillin dosage for cats is about 10 mg/kg to 25 mg/kg of body weight every 12 hours. Your veterinarian will prescribe the appropriate dosage of amoxicillin. Your cat will need to take amoxicillin for 3 to 5 days or up to a few weeks. It will depend on the type of infection your cat has as well as its weight and other conditions.

GoodRx icon

Amoxicillin is typically prescribed to cats as a liquid form that is given by mouth. The liquid form of amoxicillin is often known by the brand name Amoxi-Drop. If your cat is prescribed the liquid form, you must shake it before use and keep it cold in a refrigerator.

Your cat’s amoxicillin may be supplied to you as powder in a bottle. Using the directions on the package, mix the powder with water. Then shake well before giving it to your cat. Store the medication in your fridge and discard any unused portions after 14 days.

Amoxicillin also comes in tablets (Amoxi-Tabs) and capsules. However, the liquid form is usually easier to give to cats. So tablets and capsules are rarely prescribed. In addition, there is an injectable form of amoxicillin. But this form is typically only for veterinary use. 

Like all antibiotics, you should give amoxicillin until all the medication is gone, or as directed by your veterinarian. Even if your cat is feeling better, it is important to finish the medication as prescribed to fully eliminate the bacterial infection.

What are the common side effects of amoxicillin in cats?

In general, amoxicillin is safe and doesn’t cause many side effects. But like all antibiotics, it can cause:

If you notice these side effects in your cat, call your veterinarian for advice as soon as possible — preferably before you give the next dose. Giving your cat the medication with food can help reduce digestive side effects.

What are the most serious risks of amoxicillin for cats?

Serious side effects of amoxicillin in cats are rare. The most severe reactions occur if your cat has an allergy to penicillin antibiotics. Signs of a penicillin allergy in cats include:

  • Severe vomiting and diarrhea

  • Swollen face

  • Hives (bumps all over body)

  • Rash on ears, forehead, or belly

  • Watery eyes

  • Fever

  • Anaphylaxis, which is a severe allergic reaction that can cause difficulty breathing and collapse

If you notice any of these symptoms in your cat after it takes amoxicillin, stop giving the medication and call your veterinarian or a local emergency clinic immediately. Amoxicillin should not be given to cats who have a history of allergic reactions to penicillin antibiotics.

Does amoxicillin interact with any other cat medications?

Yes, amoxicillin can interact with other medications for cats. Depending on your cat’s condition, you shouldn’t give amoxicillin at the same time as other antibiotics, especially tetracycline antibiotics. Using these antibiotics together can reduce how well amoxicillin works. Your veterinarian will help determine the best treatment for your cat.

You also shouldn’t give amoxicillin to cats that are receiving mycophenolate, a medication for certain autoimmune conditions. Amoxicillin will lower the effectiveness of mycophenolate.

Let your veterinarian know about any vitamins or supplements you are giving your cat. Even these nonprescription substances may interfere with amoxicillin or cause adverse effects.

The bottom line

Amoxicillin is a safe and effective antibiotic that can be used to treat many types of bacterial infections in cats. Give it as prescribed. And do not stop giving the medication early, even if your cat is feeling better. If your cat has any negative reactions to amoxicillin, call your veterinarian immediately for advice.

why trust our exports reliability shield

Why trust our experts?

Sarah J. Wooten, DVM, CVJ
Dr. Sarah Wooten, DVM, CVJ, is a well-known international influencer in the veterinary and animal healthcare spaces. She has 16 years of experience in private practice and more than 15 years experience in veterinary media work.
Renée Fabian, MA
Renée Fabian is the senior pet health editor at GoodRx. She’s worked for nearly 10 years as a journalist and editor across a wide range of health and well-being topics.
Ghanasyam Bey, DVM
Reviewed by:
Ghanasyam Bey, DVM
Ghanasyam Bey, DVM, is from Cleveland, Ohio, and attended Princeton University for undergraduate studies. After a year of biology research at Duke University, he attended Ohio State College of Veterinary Medicine.

References

Brooks, W. (2022). Amoxicillin (numerous brand names). Veterinary Partner.

Gwaltney-Brant, S. M. (2019). Antibiotic use in pets. Veterinary Partner.

View All References (5)

Lappin, M. (2018). Management of bacterial and viral upper respiratory infections in cats. World Small Animal Veterinary Association Congress Proceedings.

Merck Veterinary Manual. (n.d.). Dosages of tetracyclines.

Plumb’s Veterinary Medication Guides. (n.d.). Amoxicillin/clavulanate.

Zoetis. (2019). Amoxi-Drop (amoxicillin for oral suspension), USP [package insert].

Zoetis. (2024). Amoxi-tabs- amoxicillin tablet, film coated [package insert]. DailyMed.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

Was this page helpful?

Pet Health Tips from Our Vets

Sign up for our Pet Health newsletter to receive advice for current, aspiring, and doing-their-best dog and cat owners.

By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx.